Benzene, [2-(2-methyl-1-cyclohexen-1-yl)ethyl]-

Base Information

• Chemical Name: Benzene, [2-(2-methyl-1-cyclohexen-1-yl)ethyl]-
• CAS No.: 63521-79-9
• Molecular Formula: C₁₅H₂₀
• Molecular Weight: 200.324
• Mol file: 63521-79-9.mol

Synonyms:

Chemical Property of Benzene, [2-(2-methyl-1-cyclohexen-1-yl)ethyl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzene, [2-(2-methyl-1-cyclohexen-1-yl)ethyl]-

There total 8 articles about Benzene, [2-(2-methyl-1-cyclohexen-1-yl)ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C9H15Cl → (-)-(R)-(2-(3-methylcyclohex-2-enyl)ethyl)benzene + (S)-(2-(3-methylcyclohex-2-enyl)ethyl)benzene (1215227-40-9) + 1-methyl-2-phenethyl-cyclohexene (63521-79-9)

Guidance literature:

C₉H₁₅Cl; With copper(I) thiophene-2-carboxylate; (S)-(+)-(3,5-dioxa-4-phosphacyclohepta[2,1-a;3,4-a']dinaphthalen-4-yl)-bis-[(1S)-1-(2-methoxy-phenyl)ethyl]amine; In dichloromethane; at -78 - 20 ℃; Inert atmosphere;

2-phenylethylmagnesium halide; In diethyl ether; dichloromethane; at -78 ℃; for 2h; Inert atmosphere;

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In diethyl ether; dichloromethane; at 20 ℃; for 3h; optical yield given as %ee; regioselective reaction; Inert atmosphere;

DOI:10.1021/ol100162y

Reference yield:

9-phenyl-2,7-nonanedione (63521-73-3) → 1-methyl-2-phenethyl-cyclohexene (63521-79-9)

Guidance literature:

With titanium(III) chloride; copper; zinc; In 1,2-dimethoxyethane;

DOI:10.1021/jo00435a038 DOI:10.1021/jo00411a002

Reference yield:

2-Methylcyclohexanone (583-60-8) → 1-methyl-2-phenethyl-cyclohexene (63521-79-9)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether

2: Destillation in Gegenwart von Jod

With diethyl ether;

DOI:10.1039/jr9380000672

upstream raw materials:

1-β-Phenylethyl-2-methylcyclohexanol

9-phenyl-2,7-nonanedione

phenethylmagnesium bromide

2-Methylcyclohexanone

Downstream raw materials:

4a-methyl-1.2.3.4.4a.9.10.10a-octahydro-phenanthrene