Cyclobutanemethanol

Base Information

• Chemical Name: Cyclobutanemethanol
• CAS No.: 4415-82-1
• Molecular Formula: C5H10O
• Molecular Weight: 86.1338
• Hs Code.: 29061900
• European Community (EC) Number: 224-575-4
• UNII: MUZ4H2286I
• DSSTox Substance ID: DTXSID40196057
• Nikkaji Number: J80.828H
• Wikidata: Q72459367
• Mol file: 4415-82-1.mol

Synonyms:cyclobutylcarbinol;cyclobutylmethanol

Chemical Property of Cyclobutanemethanol

Chemical Property:

• Appearance/Colour: Clear colourless liquid
• Vapor Pressure: 2.14mmHg at 25°C
• Melting Point: 68.5 °C
• Refractive Index: n20/D 1.446(lit.)
• Boiling Point: 143.499 °C at 760 mmHg
• PKA: 15.26±0.10(Predicted)
• Flash Point: 40 °C
• PSA: 20.23000
• Density: 0.961 g/cm³
• LogP: 0.77880
• Storage Temp.: Flammables area
• Water Solubility.: immiscible
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 86.073164938
• Heavy Atom Count: 6
• Complexity: 39.2

Purity/Quality:

99% ^*data from raw suppliers

Cyclobutanemethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R10:
• Hazard Codes: R10:易燃
• Statements: 10
• Safety Statements: 16-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Classes -> Alcohols and Polyols, Other
• Canonical SMILES: C1CC(C1)CO
• Uses: Cyclobutanemethanol was used in the synthesis of bicyclic lactone.

Technology Process of Cyclobutanemethanol

There total 31 articles about Cyclobutanemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

C8H18OSi → cyclobutanemethanol (4415-82-1)

Guidance literature:

With methanol; 1,3-disulfonic acid imidazolium hydrogen sulfate; at 20 ℃; for 0.0666667h; Green chemistry;

DOI:10.1016/j.molcata.2012.08.002

Reference yield: 96.0%

Cyclobutanecarboxylic acid (3721-95-7) → cyclobutanemethanol (4415-82-1)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 1.5h; Ambient temperature;

DOI:10.1021/jm00133a003

Reference yield: 53.0%

ethyl cyclobutylcarboxylate (14924-53-9) → cyclobutanemethanol (4415-82-1)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; 1) rt, 24 h, 2) reflux, 1.5 h;

upstream raw materials:

ethanol

diethyl cyclobutane-1,1-dicarboxylate

Cyclobutanecarboxylic acid

ethyl cyclobutylcarboxylate

Downstream raw materials:

(Bromomethyl)cyclobutane

Cyclopentyl bromide

cyclobutane

Cyclopentanol

Refernces

• 1、 -. "Metal complex catalysts and method for catalytically reducing carboxylic acids". Paragraph 0156; 0161; 0162; 0178; 0179. . Retrieved 2020/06/20.
• 2、 Junge, Kathrin,Wendt, Bianca,Cingolani, Andrea,Spannenberg, Anke,Wei, Zhihong,Jiao, Haijun,Beller, Matthias. "Cobalt Pincer Complexes for Catalytic Reduction of Carboxylic Acid Esters". supporting information. p. 1046 - 1052. Retrieved 2018/01/01.