3-Phenylpyruvic acid methyl ester

Base Information

• Chemical Name: 3-Phenylpyruvic acid methyl ester
• CAS No.: 6362-58-9
• Molecular Formula: C10H10O3
• Molecular Weight: 178.188
• Hs Code.: 2918300090
• Mol file: 6362-58-9.mol

Synonyms:methyl 2-oxo-3-phenylpropionate;phenyl-pyruvic acid methyl ester;3-Phenylpyruvic acid methyl ester;Pyruvic acid,phenyl-,methyl ester;methyl 3-phenyl-2-oxopropanoate;Methyl Phenylpyruvate;Phenyl-brenztraubensaeure-methylester;methyl 3-phenylpyruvate;

Chemical Property of 3-Phenylpyruvic acid methyl ester

Chemical Property:

• Melting Point: 115 °C
• Boiling Point: 152-154 °C(Press: 3 Torr)
• PSA: 43.37000
• Density: 1.143±0.06 g/cm3(Predicted)
• LogP: 0.97120

Purity/Quality:

95% ^*data from raw suppliers

Methyl2-oxo-3-phenylpropanoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Phenylpyruvic acid methyl ester

There total 25 articles about 3-Phenylpyruvic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(Z)-methyl 2-amino-3-phenylacrylate (80612-97-1) → methyl phenylpyruvate (6362-58-9)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; for 0.5h; Ambient temperature;

DOI:10.1248/cpb.32.3934

Reference yield: 95.0%

β-Aminozimtsaeureethylester (71663-73-5) → methyl phenylpyruvate (6362-58-9)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; for 0.5h; Ambient temperature;

DOI:10.1248/cpb.32.3934

Reference yield: 95.0%

(Z)-2-Amino-3-phenyl-acrylic acid isopropyl ester (95824-83-2) → methyl phenylpyruvate (6362-58-9)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; for 0.5h; Ambient temperature;

DOI:10.1248/cpb.32.3934

upstream raw materials:

methanol

phenyl-oxalacetic acid-anhydride

diazomethane

2-oxo-3-(phenyl)propionic acid

Downstream raw materials:

2-benzyl-2-hydroxy-4-oxo-3-phenyl-glutaric acid

methyl (Z)-2-acetyloxy-3-phenyl-2-propenoate

methyl 4-(4-hydroxy-5-oxo-3-phenyl-2,5-dihydro-2-furyl)butyrate

ethyl 3-(4-hydroxy-5-oxo-3-phenyl-2,5-dihydro-2-furyl)propionate