5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole

Base Information

Chemical Name:5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole
CAS No.:5300-92-5
Molecular Formula:C10H7 Br Cl N O
Molecular Weight:272.529
Hs Code.:2934999090
DSSTox Substance ID:DTXSID20201052
Nikkaji Number:J41.510C
Wikidata:Q83074238
Mol file:5300-92-5.mol

Synonyms:5300-92-5;5-(bromomethyl)-3-(4-chlorophenyl)isoxazole;5-(bromomethyl)-3-(4-chlorophenyl)-1,2-oxazole;BRN 1212727;5-Bromomethyl-3-(p-chlorophenyl)isoxazole;ISOXAZOLE, 5-BROMOMETHYL-3-(p-CHLOROPHENYL)-;C10H7BrClNO;Isoxazole, 5-(bromomethyl)-3-(4-chlorophenyl)-;C10-H7-Br-Cl-N-O;SCHEMBL3688842;DTXSID20201052;YGCXXYLQISERCR-UHFFFAOYSA-N;MFCD06738491;AKOS009096509;AB27225;LS-86511;5-bromomethyl-3-(4-chlorophenyl)isoxazole;FT-0749148;EN300-24531;5-(bromomethyl)-3-(4-chlorophenyl)-isoxazole;A21568;Isoxazole, 5-(bromomethyl)-3-(p-chlorophenyl)-;Z198974074;5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole, AldrichCPR

Suppliers and Price of 5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole Aldrich
1g
$ 333.00

Heterocyclics
5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole 97%
5g
$ 750.00

Heterocyclics
5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole 97%
1g
$ 275.00

Crysdot
5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole 95+%
250mg
$ 195.00

Crysdot
5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole 95+%
1g
$ 433.00

Chemenu
4-Bromomethyl-3-(4-chloro-phenyl)-isoxazole 95%
1g
$ 405.00

American Custom Chemicals Corporation
5-(BROMOMETHYL)-3-(4-CHLOROPHENYL)ISOXAZOLE 95.00%
5G
$ 1759.28

American Custom Chemicals Corporation
5-(BROMOMETHYL)-3-(4-CHLOROPHENYL)ISOXAZOLE 95.00%
2.5G
$ 1363.65

American Custom Chemicals Corporation
5-(BROMOMETHYL)-3-(4-CHLOROPHENYL)ISOXAZOLE 95.00%
1G
$ 925.31

AK Scientific
5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole
1g
$ 542.00

Total 10 raw suppliers

Chemical Property of 5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole

Chemical Property:

Vapor Pressure:1.68E-05mmHg at 25°C
Boiling Point:375.4°Cat760mmHg
Flash Point:180.9°C
PSA：26.03000
Density:1.582g/cm³
LogP:3.88990
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:270.93995
Heavy Atom Count:14
Complexity:185

Purity/Quality:

97% ^*data from raw suppliers

5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole Aldrich ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=NOC(=C2)CBr)Cl

Technology Process of 5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole

There total 9 articles about 5-(Bromomethyl)-3-(4-chlorophenyl)isoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 106-96-7
propargyl bromide

: 28123-63-9
4-chlorobenzohydroximoyl chloride

: 5300-92-5
5-(bromomethyl)-3-(4-chlorophenyl)-isoxazole

Guidance literature:: With 2-(2'-pyridyl)benzimidazole; copper diacetate; potassium carbonate; In water; at 20 ℃; for 3h; regioselective reaction; Green chemistry;
DOI:10.1007/s13738-017-1280-0

Reference yield: 84.0%

: 3-bromo-1-(4-chlorophenyl)but-3-en-1-one oxime

: 5300-92-5
5-(bromomethyl)-3-(4-chlorophenyl)-isoxazole

Guidance literature:: With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; In acetonitrile; at 25 ℃; Sealed tube; Inert atmosphere;
DOI:10.1021/acs.orglett.8b00967