2,2,2-Trifluoroethyl (4-methylbenzene-1-sulfonyl)carbamate

Base Information

Chemical Name:2,2,2-Trifluoroethyl (4-methylbenzene-1-sulfonyl)carbamate
CAS No.:63924-37-8
Molecular Formula:C₁₀H₁₀F₃NO₄S
Molecular Weight:297.255
Hs Code.:
DSSTox Substance ID:DTXSID40513624
Wikidata:Q82373531

Synonyms:63924-37-8;DTXSID40513624;2,2,2-Trifluoroethyl (4-methylbenzene-1-sulfonyl)carbamate

Suppliers and Price of 2,2,2-Trifluoroethyl (4-methylbenzene-1-sulfonyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2,2,2-Trifluoroethyl (4-methylbenzene-1-sulfonyl)carbamate

Chemical Property:

PSA：84.34000
LogP:3.25740
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:297.02826346
Heavy Atom Count:19
Complexity:408

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NC(=O)OCC(F)(F)F

Technology Process of 2,2,2-Trifluoroethyl (4-methylbenzene-1-sulfonyl)carbamate

There total 1 articles about 2,2,2-Trifluoroethyl (4-methylbenzene-1-sulfonyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 75-89-8
2,2,2-trifluoroethanol

: 4083-64-1
Tosyl isocyanate

: 63924-37-8
2,2,2-trifluoroethyl tosylcarbamate

Guidance literature:: In dichloromethane; at 0 - 20 ℃; for 3h;
DOI:10.1021/acs.joc.6b03089

Reference yield:

: 872-05-9,17438-89-0,25189-70-2
1-Decene

: 63924-37-8
2,2,2-trifluoroethyl tosylcarbamate

: (Z)-2,2,2-trifluoroethyl dec-2-en-1-yl(tosyl)carbamate

: (E)-2,2,2-trifluoroethyl dec-2-en-1-yl(tosyl)carbamate

: 2,2,2-trifluoroethyl dec-1-en-3-yl(tosyl)carbamate

Guidance literature:: With 1,2-bis(adamantan-1-ylsulfinyl)ethane; palladium diacetate; triethylamine; p-benzoquinone; In tert-butyl methyl ether; at 45 ℃; for 72h; Reagent/catalyst; Overall yield = 64 %; Overall yield = 69.7mg; Sealed tube;
DOI:10.1021/acs.joc.6b03089