N-(2-hydroxyethyl)-3-chloroaniline

Base Information

Chemical Name:N-(2-hydroxyethyl)-3-chloroaniline
CAS No.:6393-19-7
Molecular Formula:C8H10ClNO
Molecular Weight:171.626
Hs Code.:
DSSTox Substance ID:DTXSID70485587
Wikidata:Q82324887

Synonyms:6393-19-7;N-(2-hydroxyethyl)-3-chloroaniline;2-(3-chlorophenylamino)ethanol;SCHEMBL2470288;DTXSID70485587;SOFUHSYORPZNQN-UHFFFAOYSA-N;AKOS000253766;N-(2-Hydroxy-ethyl)-3-chloro-aniline;2-[(3-CHLOROPHENYL)AMINO]ETHANOL

Suppliers and Price of N-(2-hydroxyethyl)-3-chloroaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of N-(2-hydroxyethyl)-3-chloroaniline

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:171.0450916
Heavy Atom Count:11
Complexity:110

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)Cl)NCCO

Technology Process of N-(2-hydroxyethyl)-3-chloroaniline

There total 7 articles about N-(2-hydroxyethyl)-3-chloroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.5%

: 75-21-8,99932-75-9
oxirane

: 108-42-9
3-chloro-aniline

: 6393-19-7
3-chloro-N-hydroxyethyl aniline

Guidance literature:: With iron(III) chloride; In ethyl acetate; at 10 ℃; for 5h;

Reference yield:

: 108-42-9
3-chloro-aniline

: 107-07-3
2-chloro-ethanol

: 6393-19-7
3-chloro-N-hydroxyethyl aniline

Guidance literature:: DOI:10.1021/ja01638a063

Reference yield:

: 627-11-2
2-Chloroethyl chloroformate

: 108-42-9
3-chloro-aniline

: 6393-19-7
3-chloro-N-hydroxyethyl aniline

Guidance literature:: 2-Chloroethyl chloroformate; 3-chloro-aniline; With pyridine; In dichloromethane; at 20 ℃; Inert atmosphere;

With potassium hydroxide; In ethanol; at 90 ℃; for 5h; Inert atmosphere;
DOI:10.1002/anie.201602020