CHEMBRDG-BB 9071951

Base Information

• Chemical Name: CHEMBRDG-BB 9071951
• CAS No.: 64001-12-3
• Molecular Formula: C7H6N4O
• Molecular Weight: 162.151
• Hs Code.: 2933990090
• Mol file: 64001-12-3.mol

Synonyms:4-(tetrazol-2-yl)phenol;

Chemical Property of CHEMBRDG-BB 9071951

Chemical Property:

• Vapor Pressure: 5.3E-06mmHg at 25°C
• Boiling Point: 370.2oC at 760 mmHg
• Flash Point: 177.7oC
• PSA: 63.83000
• Density: 1.46g/cm3
• LogP: 0.36790

Purity/Quality:

98% ^*data from raw suppliers

4-(2H-tetrazol-2-yl)phenol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CHEMBRDG-BB 9071951

There total 7 articles about CHEMBRDG-BB 9071951 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4-aminophenyl)-2H-tetrazole (52708-35-7) → 4-(2H-tetrazol-2-yl)phenol (64001-12-3)

Guidance literature:

With sulfuric acid; sodium nitrite; In water; at 0 - 120 ℃; for 1.5h;

Reference yield:

C10H14N4OSi → 4-(2H-tetrazol-2-yl)phenol (64001-12-3)

Guidance literature:

With cesium fluoride; In tetrahydrofuran; methanol; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1016/j.tetlet.2016.02.102

Reference yield:

2-(4-nitro-phenyl)-2H-tetrazole (52708-38-0) → 4-(2H-tetrazol-2-yl)phenol (64001-12-3)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogen / palladium 10% on activated carbon / ethanol; ethyl acetate / 2 h / Inert atmosphere

2: sulfuric acid; sodium nitrite / water / 1.5 h / 0 - 120 °C

With sulfuric acid; hydrogen; sodium nitrite; palladium 10% on activated carbon; In ethanol; water; ethyl acetate;

upstream raw materials:

2-(4-aminophenyl)-2H-tetrazole

4-amino-phenol

2-(4-nitro-phenyl)-2H-tetrazole

4-Fluoronitrobenzene

Downstream raw materials:

2-methoxy-5-tetrazol-2-ylbenzaldehyde

2-hydroxy-5-tetrazol-2-ylbenzaldehyde

Refernces

• 1、 -. "SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT". Page/Page column 74-75. . Retrieved 2009/12/02.