4-(2H-Tetrazol-2-yl)benzenamine

Base Information

• Chemical Name: 4-(2H-Tetrazol-2-yl)benzenamine
• CAS No.: 52708-35-7
• Molecular Formula: C7H7N5
• Molecular Weight: 161.166
• Hs Code.: 2933990090
• Mol file: 52708-35-7.mol

Synonyms:4-(2H-Tetraazol-2-yl)phenylamine;4-(1,2,3,4-tetraazol-2-yl)phenylamine;4-(2H-Tetraazol-2-yl)aniline;Benzenamine,4-(2H-tetrazol-2-yl);

Chemical Property of 4-(2H-Tetrazol-2-yl)benzenamine

Chemical Property:

• PSA: 69.62000
• LogP: 0.82570

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(2H-Tetrazol-2-yl)benzenamine

There total 5 articles about 4-(2H-Tetrazol-2-yl)benzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2-(4-nitro-phenyl)-2H-tetrazole (52708-38-0) → 2-(4-aminophenyl)-2H-tetrazole (52708-35-7)

Guidance literature:

With palladium on activated charcoal; hydrogen; In methanol; at 20 ℃; for 24h;

Reference yield: 44.0%

1H-tetrazole (288-94-8) + 4-Fluoronitrobenzene (350-46-9,178603-76-4) → 4-tetrazol-1-yl-phenylamine (14213-13-9) + 2-(4-aminophenyl)-2H-tetrazole (52708-35-7)

Guidance literature:

1H-tetrazole; 4-Fluoronitrobenzene; With potassium carbonate; In N,N-dimethyl-formamide; at 70 - 75 ℃; for 10h;

With iron(III) chloride; pyrographite; hydrazine hydrate; In tetrahydrofuran; methanol; at 50 ℃; for 10h;

DOI:10.1248/cpb.48.1935

Reference yield:

1H-tetrazole (288-94-8) + 4-Fluoronitrobenzene (350-46-9,178603-76-4) → 2-(4-aminophenyl)-2H-tetrazole (52708-35-7)

Guidance literature:

1H-tetrazole; 4-Fluoronitrobenzene; With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃;

With platinum(IV) oxide; hydrogen; In tetrahydrofuran; at 20 ℃;

upstream raw materials:

1H-tetrazole

4-Fluoronitrobenzene

2-(4-nitro-phenyl)-2H-tetrazole

Downstream raw materials:

4-(2H-tetrazol-2-yl)phenol

4-(2H-tetrazol-2-yl)benzenesulfonyl chloride

1-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-3-[4-(2H-2-tetrazolyl)phenyl]-2(1H,3H)-imidazolone

1-(2,2-diethoxy-ethyl)-3-(4-tetrazol-2-yl-phenyl)-urea