[4-(Benzyloxy)-5-methoxy-2-nitrophenyl]methanol

Base Information

Chemical Name:[4-(Benzyloxy)-5-methoxy-2-nitrophenyl]methanol
CAS No.:64154-63-8
Molecular Formula:C15H15NO5
Molecular Weight:289.288
Hs Code.:
DSSTox Substance ID:DTXSID80589686
Wikidata:Q82483201

Synonyms:64154-63-8;[4-(Benzyloxy)-5-methoxy-2-nitrophenyl]methanol;SCHEMBL13224057;DTXSID80589686;AKOS009116119;DB-110750

Suppliers and Price of [4-(Benzyloxy)-5-methoxy-2-nitrophenyl]methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of [4-(Benzyloxy)-5-methoxy-2-nitrophenyl]methanol

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:289.09502258
Heavy Atom Count:21
Complexity:327

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C(=C1)CO)[N+](=O)[O-])OCC2=CC=CC=C2

Technology Process of [4-(Benzyloxy)-5-methoxy-2-nitrophenyl]methanol

There total 5 articles about [4-(Benzyloxy)-5-methoxy-2-nitrophenyl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 2426-84-8
4-(benzyloxy)-5-methoxy-2-nitrobenzaldehyde

: 64154-63-8
(4-(benzyloxy)-5-methoxy-2-nitrophenyl)methanol

Guidance literature:: With sodium tetrahydroborate; In methanol; at 20 ℃; for 0.25h;
DOI:10.1039/c9cc09449k

Reference yield: 52.0%

: 33693-48-0
4-benzyloxy-3-methoxybenzyl alcohol

: 64154-63-8
(4-(benzyloxy)-5-methoxy-2-nitrophenyl)methanol

Guidance literature:: With copper(II) nitrate monohydrate; acetic anhydride; at 0 - 20 ℃;

Reference yield:

: 100-39-0
benzyl bromide

: 64154-63-8
(4-(benzyloxy)-5-methoxy-2-nitrophenyl)methanol

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / ethanol / Inert atmosphere

2: nitric acid / 1.25 h / 0 °C

3: sodium tetrahydroborate / ethanol; tetrahydrofuran / 2 h / 0 - 20 °C

With sodium tetrahydroborate; nitric acid; potassium carbonate; In tetrahydrofuran; ethanol;
DOI:10.1039/c8ob00946e