1,3-Dihydro-5-chloro-3-(4-(dimethylamino)phenyl)-1-methyl-2H-benzimidazol-2-one

Base Information

Chemical Name:1,3-Dihydro-5-chloro-3-(4-(dimethylamino)phenyl)-1-methyl-2H-benzimidazol-2-one
CAS No.:79759-83-4
Molecular Formula:C₁₆H₁₆ClN₃O
Molecular Weight:301.776
Hs Code.:
DSSTox Substance ID:DTXSID701000715
Wikidata:Q82994418

Synonyms:BRN 5587126;1,3-Dihydro-5-chloro-3-(4-(dimethylamino)phenyl)-1-methyl-2H-benzimidazol-2-one;2H-Benzimidazol-2-one, 1,3-dihydro-5-chloro-3-(4-(dimethylamino)phenyl)-1-methyl-;79759-83-4;DTXSID701000715;LS-33303;5-Chloro-3-[4-(dimethylamino)phenyl]-1-methyl-1,3-dihydro-2H-benzimidazol-2-one

Suppliers and Price of 1,3-Dihydro-5-chloro-3-(4-(dimethylamino)phenyl)-1-methyl-2H-benzimidazol-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,3-Dihydro-5-chloro-3-(4-(dimethylamino)phenyl)-1-methyl-2H-benzimidazol-2-one

Chemical Property:

Vapor Pressure:5.32E-09mmHg at 25°C
Boiling Point:469.9°Cat760mmHg
Flash Point:238°C
Density:1.304g/cm³
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:301.0981898
Heavy Atom Count:21
Complexity:395

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=C(C=C(C=C2)Cl)N(C1=O)C3=CC=C(C=C3)N(C)C

Technology Process of 1,3-Dihydro-5-chloro-3-(4-(dimethylamino)phenyl)-1-methyl-2H-benzimidazol-2-one

There total 3 articles about 1,3-Dihydro-5-chloro-3-(4-(dimethylamino)phenyl)-1-methyl-2H-benzimidazol-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 79759-73-2
5-Chloro-1-methyl-3-(4-nitro-phenyl)-1,3-dihydro-benzoimidazol-2-one

: 79759-83-4
5-Chloro-3-(4-dimethylamino-phenyl)-1-methyl-1,3-dihydro-benzoimidazol-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / 37 percent aq. HCl, zinc / ethanol / 1 h

2: 43 percent / K₂CO₃ / dimethylformamide / 12 h / Heating

With hydrogenchloride; potassium carbonate; zinc; In ethanol; N,N-dimethyl-formamide;

Reference yield:

: 586-78-7
para-nitrophenyl bromide

: 79759-83-4
5-Chloro-3-(4-dimethylamino-phenyl)-1-methyl-1,3-dihydro-benzoimidazol-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / AcOK, Cu, CuCl / bis-(2-methoxy-ethyl) ether / 10 h / Heating

2: 85 percent / 37 percent aq. HCl, zinc / ethanol / 1 h

3: 43 percent / K₂CO₃ / dimethylformamide / 12 h / Heating

With hydrogenchloride; potassium acetate; copper; potassium carbonate; copper(l) chloride; zinc; In ethanol; diethylene glycol dimethyl ether; N,N-dimethyl-formamide;

Reference yield:

: 15965-71-6
5-chloro-1,3-dihydro-1-methyl-2H-benzimidazol-2-one

: 79759-83-4
5-Chloro-3-(4-dimethylamino-phenyl)-1-methyl-1,3-dihydro-benzoimidazol-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / AcOK, Cu, CuCl / bis-(2-methoxy-ethyl) ether / 10 h / Heating

2: 85 percent / 37 percent aq. HCl, zinc / ethanol / 1 h

3: 43 percent / K₂CO₃ / dimethylformamide / 12 h / Heating

With hydrogenchloride; potassium acetate; copper; potassium carbonate; copper(l) chloride; zinc; In ethanol; diethylene glycol dimethyl ether; N,N-dimethyl-formamide;