4-Phenylthiazol-2-amine monohydrobromide

Base Information

• Chemical Name: 4-Phenylthiazol-2-amine monohydrobromide
• CAS No.: 34161-31-4
• Molecular Formula: C9H8 N2 S . Br H
• Molecular Weight: 257.154
• Hs Code.: 2934100090
• European Community (EC) Number: 251-859-5
• DSSTox Substance ID: DTXSID60187765
• Mol file: 34161-31-4.mol

Synonyms:4-Phenylthiazol-2-amine monohydrobromide;34161-31-4;EINECS 251-859-5;2-amino-4-phenylthiazole hydrobromide;4-phenyl-1,3-thiazol-2-amine,hydrobromide;C9H8N2S.BrH;C9-H8-N2-S.Br-H;SCHEMBL7128948;DTXSID60187765;AKOS003745871;2-amino-4-phenylthiazole hydrobromide, AldrichCPR

Chemical Property of 4-Phenylthiazol-2-amine monohydrobromide

Chemical Property:

• Boiling Point: 363.4°Cat760mmHg
• Flash Point: 173.6°C
• PSA: 67.15000
• Density: g/cm³
• LogP: 3.93160
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 255.96698
• Heavy Atom Count: 13
• Complexity: 146

Purity/Quality:

99% ^*data from raw suppliers

2-AMINO-4-PHENYLTHIAZOLE HYDROBROMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CSC(=N2)N.Br

Technology Process of 4-Phenylthiazol-2-amine monohydrobromide

There total 3 articles about 4-Phenylthiazol-2-amine monohydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

thiourea (17356-08-0) + α-bromoacetophenone (70-11-1) → 2-amino-4-phenyl-thiazole hydrobromide (34161-31-4)

Guidance literature:

at 20 ℃; for 0.5h;

Reference yield: 92.0%

2-bromo-1-phenylethylidenemalononitrile (4651-78-9) + thiourea (17356-08-0) → 2-amino-4-phenyl-thiazole hydrobromide (34161-31-4)

Guidance literature:

In ethanol;

DOI:10.1016/S0040-4039(00)94750-6

Reference yield: 20.0%

1-bromo-2-phenylglyoxal 1-phenyhydrazone (55716-62-6) → 3,6-Dibenzoyl-1,4-dihydro-1,4-diphenyl-1,2,4,5-tetrazine (59255-39-9) + 2-amino-4-phenyl-thiazole hydrobromide (34161-31-4) + 6-phenylazo-3,5-diphenylimidazo<2,1-b>thiazole (87309-58-8)

Guidance literature:

With 2-Amino-4-phenylthiazole; In ethanol; Heating;

upstream raw materials:

1-bromo-2-phenylglyoxal 1-phenyhydrazone

2-bromo-1-phenylethylidenemalononitrile

thiourea

α-bromoacetophenone

Downstream raw materials:

N⁵-benzylidene-4-phenyl-thiazole-2,5-diyldiamine

N,4-diphenyl-1,3-thiazol-2-amine

LUF₅₇₂₈

2-[(benzoyl)amino]-4-(phenyl)thiazole