2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-3-phenyl-propanoic Acid

Base Information

Chemical Name:2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-3-phenyl-propanoic Acid
CAS No.:64263-83-8
Molecular Formula:C15H21NO4
Molecular Weight:279.336
Hs Code.:
European Community (EC) Number:822-726-4

Synonyms:64263-83-8;2-{[(tert-butoxy)carbonyl](methyl)amino}-3-phenylpropanoic acid;Boc-N-methyl-DL-phenylalanine;2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-3-phenyl-propanoic Acid;2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-3-phenylpropanoic acid;N-Boc-N-methyl-L-phenylalanine;2-([(tert-Butoxy)carbonyl](methyl)amino)-3-phenylpropanoic acid;MFCD00038754;MFCD00151890;2-[methyl-[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3-phenylpropanoic acid;boc-methyl-dl-phenylalanine;SCHEMBL2476924;AJGJINVEYVTDNH-UHFFFAOYSA-N;N-BOC-N-methyl-d,I-phenylalanine;N-BOC-N-methyl-d,l-phenylalanine;AKOS013465575;SY030028;SY065419;FT-0629964;FT-0629967;FT-0639387;EN300-198878;F78663;A823754;A826766;N-(TERT-BUTOXYCARBONYL)-N-METHYLPHENYLALANINE;Z1200999386;2-(tert-butoxycarbonyl(methyl)amino)-3-phenylpropanoic acid;2-{[(tert-butoxy)carbonyl](methyl)amino}-3-phenylpropanoicacid;2-[N-methyl-N-(tert-butoxycarbonyl)-amino]-3-phenyl-propionic acid

Suppliers and Price of 2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-3-phenyl-propanoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-3-phenyl-propanoic Acid

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:279.14705815
Heavy Atom Count:20
Complexity:342

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N(C)C(CC1=CC=CC=C1)C(=O)O

Technology Process of 2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-3-phenyl-propanoic Acid

There total 10 articles about 2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-3-phenyl-propanoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 18942-49-9
Boc-D-Phe-OH

: 74-88-4
methyl iodide

: 37553-65-4,64263-83-8,85466-66-6
N-tert-butoxycarbonyl-N-methyl-D-phenylalanine

Guidance literature:: With sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1002/hlca.201200519

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 170642-33-8
(S,S)-pseudoephedrine N-methyl-D-phenylalaninamide

: 90-82-4,7009-81-6,90-83-5,6912-63-6
pseudoephedrine

: 37553-65-4,64263-83-8,85466-66-6
N-tert-butoxycarbonyl-N-methyl-D-phenylalanine

Guidance literature:: With sodium hydroxide; Yield given. Multistep reaction; 1.) methanol, reflux, 24 h;
DOI:10.1021/ja00137a034

Reference yield:

: 185508-99-0
(S)-N-((1R,2R)-2-Hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-2-methylamino-3-phenyl-propionamide

: 37553-65-4,64263-83-8,85466-66-6
N-tert-butoxycarbonyl-N-methyl-D-phenylalanine

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH / H₂O / 18 h / Heating

With sodium hydroxide; In water;
DOI:10.1021/ja9624073