Flemiculosin

Base Information

Chemical Name:Flemiculosin
CAS No.:89354-00-7
Molecular Formula:C25H24O4
Molecular Weight:388.463
Hs Code.:
NSC Number:381605
DSSTox Substance ID:DTXSID30419626
Nikkaji Number:J193.272A
Wikidata:Q76306100
Metabolomics Workbench ID:26708

Synonyms:FLEMICULOSIN;89354-00-7;NSC381605;DTXSID30419626;LMPK12120232;NSC-381605;6-cinnamoyl-5-hydroxy-2,2,8,8-tetramethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran

Suppliers and Price of Flemiculosin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Flemiculosin

Chemical Property:

Vapor Pressure:1.45E-14mmHg at 25°C
Boiling Point:591°C at 760 mmHg
Flash Point:203.9°C
PSA：55.76000
Density:1.186g/cm³
LogP:5.65670
XLogP3:5.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:388.16745924
Heavy Atom Count:29
Complexity:710

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C=CC2=C(C(=C3C(=C2O1)C=CC(O3)(C)C)C(=O)C=CC4=CC=CC=C4)O)C
Isomeric SMILES:CC1(C=CC2=C(C(=C3C(=C2O1)C=CC(O3)(C)C)C(=O)/C=C/C4=CC=CC=C4)O)C

Technology Process of Flemiculosin

There total 3 articles about Flemiculosin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 31380-12-8
1-(5-hydroxy-2,2,8,8-tetramethyl-2,8-dihydropyrano[2,3-f]chromen-6-yl)ethanone

: 100-52-7
benzaldehyde

: 89354-00-7
(E)-1-(5-hydroxy-2,2,8,8-tetramethyl-2H,8H-pyrano [2,3-f]chromen-6-yl)-3-phenylprop-2-en-1-one

Guidance literature:: With potassium hydroxide; In ethanol; water; at 20 ℃; for 6h;
DOI:10.1080/00304940609355985

Reference yield:

: 1111-97-3
3-chloro-3-methylbut-1-yne

: 89354-00-7
(E)-1-(5-hydroxy-2,2,8,8-tetramethyl-2H,8H-pyrano [2,3-f]chromen-6-yl)-3-phenylprop-2-en-1-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: KI; K₂CO₃; CuI / acetone / 3 h / Heating

1.2: 40 percent / N,N-dimethylaniline / dimethylformamide / 2 h / 140 °C

2.1: 90 percent / KOH / ethanol; H₂O / 6 h / 20 °C

With potassium hydroxide; copper(l) iodide; potassium carbonate; potassium iodide; In ethanol; water; acetone;
DOI:10.1080/00304940609355985

Reference yield:

: 480-66-0,67471-34-5
2,4,6-trihydroxyacetophenone

: 89354-00-7
(E)-1-(5-hydroxy-2,2,8,8-tetramethyl-2H,8H-pyrano [2,3-f]chromen-6-yl)-3-phenylprop-2-en-1-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: KI; K₂CO₃; CuI / acetone / 3 h / Heating

1.2: 40 percent / N,N-dimethylaniline / dimethylformamide / 2 h / 140 °C

2.1: 90 percent / KOH / ethanol; H₂O / 6 h / 20 °C

With potassium hydroxide; copper(l) iodide; potassium carbonate; potassium iodide; In ethanol; water; acetone;
DOI:10.1080/00304940609355985