Sulfaclozine

Base Information

Chemical Name:Sulfaclozine
CAS No.:102-65-8
Molecular Formula:C10H9ClN4O2S
Molecular Weight:284.726
Hs Code.:2935009090
European Community (EC) Number:203-044-0
UNII:69YP7Z48CW
DSSTox Substance ID:DTXSID60144515
Nikkaji Number:J20.456K
Wikidata:Q27264391
NCI Thesaurus Code:C72849
ChEMBL ID:CHEMBL2105493
Mol file:102-65-8.mol

Synonyms:Esb-3;Esb3;sulfaclozine;sulfatyf

Suppliers and Price of Sulfaclozine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Sulfachloropyrazine
100mg
$ 140.00

Sigma-Aldrich
Sulfaclozine sodium VETRANAL?, analytical standard
100 mg
$ 64.10

Crysdot
Sulfaclozine 98+%
100mg
$ 87.00

ChemScene
Sulfaclozine
100mg
$ 50.00

Biorbyt Ltd
Sulfaclozine
100 μg
$ 635.80

Biorbyt Ltd
Sulfaclozine
50 μg
$ 425.00

Biorbyt Ltd
Sulfaclozine
500 μg
$ 957.10

Arctom
Sulfaclozine ≥98%
1g
$ 98.00

Arctom
Sulfaclozine ≥98%
250mg
$ 39.00

Arctom
Sulfaclozine ≥98%
100mg
$ 26.00

Total 175 raw suppliers

Chemical Property of Sulfaclozine

Chemical Property:

Appearance/Colour:Slightly yellow crystal powder
Melting Point:234.8-235.4 °C
Boiling Point:495.7 °C at 760 mmHg
PKA:4.83±0.10(Predicted)
Flash Point:253.6 °C
PSA：106.35000
Density:1.588 g/cm³
LogP:3.24800
Storage Temp.:2-8°C(protect from light)
Solubility.:DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:284.0134744
Heavy Atom Count:18
Complexity:365

Purity/Quality:

99% ^*data from raw suppliers

Sulfachloropyrazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1N)S(=O)(=O)NC2=CN=CC(=N2)Cl
Uses Sulfachloropyrazine sodium monohydrate is an antiprotozoal useful in coccidiosis research.

Technology Process of Sulfaclozine

There total 3 articles about Sulfaclozine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: N-(6-chloropyrazin-2-yl)-4-nitrobenzenesulfonamide

: 102-65-8,27890-59-1
4-amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide

Guidance literature:: With tin(II) chloride dihdyrate; In ethanol; at 80 ℃; for 0.5h;
DOI:10.3390/molecules25010138

Reference yield:

: 98-74-8
4-Nitrobenzenesulfonyl chloride

: 102-65-8,27890-59-1
4-amino-N-(6-chloropyrazin-2-yl)benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride; pyridine / acetone / 20 °C / Sealed tube

2: tin(II) chloride dihdyrate / ethanol / 0.5 h / 80 °C

With pyridine; hydrogenchloride; tin(II) chloride dihdyrate; In ethanol; acetone;
DOI:10.3390/molecules25010138