Methanone, benzo[b]thien-3-ylphenyl-

Base Information

• Chemical Name: Methanone, benzo[b]thien-3-ylphenyl-
• CAS No.: 6454-03-1
• Molecular Formula: C15H10OS
• Molecular Weight: 238.31
• Mol file: 6454-03-1.mol

Synonyms:3-benzoylbenzo[b]thiophene;benzo[b]thiophen-3-yl-phenyl-methanone;3-benzothienyl(phenyl)methanone;benzo[b]thien-3-ylphenyl-methanone;Benzo[b]thiophen-3-yl-phenyl-keton;benzo[b]thiophen-3-yl-phenyl ketone;

Chemical Property of Methanone, benzo[b]thien-3-ylphenyl-

Chemical Property:

• Melting Point: 53 °C
• PSA: 45.31000
• LogP: 4.13230

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methanone, benzo[b]thien-3-ylphenyl-

There total 20 articles about Methanone, benzo[b]thien-3-ylphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-benzothienyl(phenyl)methanol (65628-41-3) → benzo[b]thiophen-3-yl(phenyl)methanone (6454-03-1)

Guidance literature:

With dimanganese decacarbonyl; In toluene; at 120 ℃; Sealed tube;

DOI:10.1039/c9gc02446h

Reference yield: 95.0%

benzothiophene-3-carboxaldehyde (5381-20-4) + phenylboronic acid (98-80-6) → benzo[b]thiophen-3-yl(phenyl)methanone (6454-03-1)

Guidance literature:

benzothiophene-3-carboxaldehyde; phenylboronic acid; With 1-(2,6-diisopropylphenyl)-3-(2-(phenylthio)phenyl)-4,5-dihydroimidazolinium chloride; bis(η3-allyl-μ-chloropalladium(II)); caesium carbonate; In 1,4-dioxane; at 100 ℃; for 1h; Inert atmosphere;

With ortho-methylphenyl iodide; In 1,4-dioxane; at 100 ℃; for 15h; Inert atmosphere;

DOI:10.1002/ejoc.201300269

Reference yield: 89.0%

3-iodobenzo[b]thiophene (36748-88-6) + carbon monoxide (201230-82-2) + phenylboronic acid (98-80-6) → benzo[b]thiophen-3-yl(phenyl)methanone (6454-03-1)

Guidance literature:

With potassium carbonate; bis-triphenylphosphine-palladium(II) chloride; In various solvent(s); at 80 ℃; for 5h;

DOI:10.1016/S0040-4039(00)60409-4

upstream raw materials:

benzoyl chloride

Benzo[b]thiophene

3-iodobenzo[b]thiophene

carbon monoxide