1-[(2-Fluorophenyl)methyl]-3-(3-methoxyphenyl)-1-(oxolan-2-ylmethyl)thiourea

Base Information

Chemical Name:1-[(2-Fluorophenyl)methyl]-3-(3-methoxyphenyl)-1-(oxolan-2-ylmethyl)thiourea
CAS No.:6175-48-0
Molecular Formula:C20H23FN2O2S
Molecular Weight:156.268
Hs Code.:
DSSTox Substance ID:DTXSID50411405

Synonyms:1-[(2-fluorophenyl)methyl]-3-(3-methoxyphenyl)-1-(oxolan-2-ylmethyl)thiourea;6175-48-0;DTXSID50411405

Suppliers and Price of 1-[(2-Fluorophenyl)methyl]-3-(3-methoxyphenyl)-1-(oxolan-2-ylmethyl)thiourea

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-[(2-Fluorophenyl)methyl]-3-(3-methoxyphenyl)-1-(oxolan-2-ylmethyl)thiourea

Chemical Property:

Vapor Pressure:4.17E-10mmHg at 25°C
Boiling Point:499.4°Cat760mmHg
Flash Point:255.8°C
Density:1.253g/cm³
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:374.14642732
Heavy Atom Count:26
Complexity:454

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=C1)NC(=S)N(CC2CCCO2)CC3=CC=CC=C3F

Technology Process of 1-[(2-Fluorophenyl)methyl]-3-(3-methoxyphenyl)-1-(oxolan-2-ylmethyl)thiourea

There total 3 articles about 1-[(2-Fluorophenyl)methyl]-3-(3-methoxyphenyl)-1-(oxolan-2-ylmethyl)thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 71-41-0
pentan-1-ol

: 107-87-9
2-Pentanone

: 624-16-8
decan-4-one

: 6175-48-0
3-ethyloctan-2-one

: 64235-55-8
(E)-dec-5-en-4-one

Guidance literature:: With [Cp*₂Ir₂(μ-N,N′-bis(5-tert-butyl-4-hydroxy-2-methylphenyl)oxalamidato)Cl₂]; calcium hydroxide; at 140 ℃; for 23h; under 750.075 - 2250.23 Torr; Catalytic behavior; Autoclave; Inert atmosphere;
DOI:10.1021/acs.oprd.0c00362

Reference yield: 45.0%

: 999-64-4
3-bromooctane

: 75-36-5
acetyl chloride

: 6175-48-0
3-ethyloctan-2-one

Guidance literature:: 3-bromooctane; With ethylmagnesium iodide; copper(l) iodide; zinc; In diethyl ether; at 35 ℃; for 48h;

acetyl chloride; In diethyl ether; for 1h;
DOI:10.1023/A:1025684302325