Methyl 2-bromo-3-fluorobenzoate

Base Information

Chemical Name:Methyl 2-bromo-3-fluorobenzoate
CAS No.:647020-71-1
Molecular Formula:C8H6BrFO2
Molecular Weight:233.037
Hs Code.:2916399090
DSSTox Substance ID:DTXSID70479860
Wikidata:Q82314163
Mol file:647020-71-1.mol

Synonyms:Methyl 2-bromo-3-fluorobenzoate;647020-71-1;2-Bromo-3-fluorobenzoic acid methyl ester;MFCD10000921;Benzoic acid, 2-bromo-3-fluoro-, methyl ester;SCHEMBL1180154;UDCCTNIBELHUQN-UHFFFAOYSA-;DTXSID70479860;UDCCTNIBELHUQN-UHFFFAOYSA-N;XAB02071;2-Bromo-3-fluorobenzoicacidmethylester;AKOS017556454;PS-11665;CS-0096404;FT-0720181;D75737;EN300-749074;2-Bromo-3-fluorobenzoic acid methyl ester, AldrichCPR;InChI=1/C8H6BrFO2/c1-12-8(11)5-3-2-4-6(10)7(5)9/h2-4H,1H3

Suppliers and Price of Methyl 2-bromo-3-fluorobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Bromo-3-fluorobenzoicacidmethylester
1g
$ 460.00

SynQuest Laboratories
2-Bromo-3-fluorobenzoic acid methyl ester
1 g
$ 304.00

SynQuest Laboratories
2-Bromo-3-fluorobenzoic acid methyl ester
250 mg
$ 136.00

SynQuest Laboratories
2-Bromo-3-fluorobenzoic acid methyl ester
5 g
$ 1056.00

Crysdot
2-Bromo-3-fluorobenzoicacidmethylester 95+%
5g
$ 790.00

Chemenu
2-Bromo-3-fluorobenzoicacidmethylester 95%
5g
$ 746.00

AOBChem
2-Bromo-3-fluorobenzoicacidmethylester 97%
5g
$ 682.00

AOBChem
2-Bromo-3-fluorobenzoicacidmethylester 97%
500mg
$ 136.00

American Custom Chemicals Corporation
2-BROMO-3-FLUOROBENZOIC ACID METHYL ESTER 95.00%
5MG
$ 498.66

Ambeed
Methyl2-bromo-3-fluorobenzoate 98%
250mg
$ 36.00

Total 2 raw suppliers

Chemical Property of Methyl 2-bromo-3-fluorobenzoate

Chemical Property:

Vapor Pressure:0.0237mmHg at 25°C
Boiling Point:248.8oC at 760 mmHg
Flash Point:104.3oC
PSA：26.30000
Density:1.577g/cm3
LogP:2.37480
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:231.95352
Heavy Atom Count:12
Complexity:174

Purity/Quality:

99% ^*data from raw suppliers

2-Bromo-3-fluorobenzoicacidmethylester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=C(C(=CC=C1)F)Br

Technology Process of Methyl 2-bromo-3-fluorobenzoate

There total 5 articles about Methyl 2-bromo-3-fluorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 67-56-1
methanol

: 132715-69-6
2-bromo-3-fluoro-benzoic acid

: 647020-71-1
2-bromo-3-fluorobenzoic acid methyl ester

Guidance literature:: With sulfuric acid; Reflux;

Reference yield: 90.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 132715-69-6
2-bromo-3-fluoro-benzoic acid

: 647020-71-1
2-bromo-3-fluorobenzoic acid methyl ester

Guidance literature:: In diethyl ether; at 25 ℃;
DOI:10.1055/s-2005-861787

Reference yield:

: 851368-08-6
1-bromo-2-fluoro-6-iodobenzene

: 647020-71-1
2-bromo-3-fluorobenzoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: butylmagnesium chloride / tetrahydrofuran / 0.25 h / -75 °C

1.2: 90 percent / tetrahydrofuran

2.1: 90 percent / diethyl ether / 25 °C

With butyl magnesium bromide; In tetrahydrofuran; diethyl ether;
DOI:10.1055/s-2005-861787