Ethyl 5-(benzyloxy)-3-oxopentanoate

Base Information

Chemical Name:Ethyl 5-(benzyloxy)-3-oxopentanoate
CAS No.:64714-79-0
Molecular Formula:C14H18O4
Molecular Weight:250.295
Hs Code.:
DSSTox Substance ID:DTXSID80442161
Nikkaji Number:J1.605.705C
Wikidata:Q82259282

Synonyms:ethyl 5-(benzyloxy)-3-oxopentanoate;64714-79-0;Ethyl3-Oxo-5-(phenylmethoxy)-pentanoicAcidEster;ethyl 3-oxo-5-phenylmethoxypentanoate;SCHEMBL3105598;Pentanoic acid, 3-oxo-5-(phenylmethoxy)-, ethyl ester;DTXSID80442161;ethyl5-(benzyloxy)-3-oxopentanoate;5-(Benzyloxy)-3-oxovaleric acid ethyl ester;FT-0712075

Suppliers and Price of Ethyl 5-(benzyloxy)-3-oxopentanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Ethyl 5-(benzyloxy)-3-oxopentanoate

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:250.12050905
Heavy Atom Count:18
Complexity:257

Purity/Quality:: 98%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC(=O)CCOCC1=CC=CC=C1

Technology Process of Ethyl 5-(benzyloxy)-3-oxopentanoate

There total 3 articles about Ethyl 5-(benzyloxy)-3-oxopentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 3587-60-8
Benzyloxymethyl chloride

: 141-97-9
ethyl acetoacetate

: 64714-79-0
5-benzyloxy-3-oxo-pentanoic acid ethyl ester

Guidance literature:: Benzyloxymethyl chloride; ethyl acetoacetate; With sodium hydride; In tetrahydrofuran; mineral oil; at -10 - 0 ℃; for 0.166667h; Inert atmosphere;

With n-butyllithium; In tetrahydrofuran; hexane; mineral oil; at -10 - 0 ℃; for 0.166667h;

Benzyloxymethyl chloride; In tetrahydrofuran; hexane; mineral oil; for 0.5h;

Reference yield:

: 4799-68-2
3-benzyloxypropan-1-ol

: 64714-79-0
5-benzyloxy-3-oxo-pentanoic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

2: SnCl₂ / CH₂Cl₂

With tin(ll) chloride; In dichloromethane; 1: Oxidation / 2: Substitution;
DOI:10.1021/jo9910987