(4-Methylphenyl)methanesulfonamide

Base Information

Chemical Name:(4-Methylphenyl)methanesulfonamide
CAS No.:64732-34-9
Molecular Formula:C8H11NO2S
Molecular Weight:185.247
Hs Code.:2935009090
European Community (EC) Number:871-689-0
DSSTox Substance ID:DTXSID20599022
Nikkaji Number:J2.149.483F
Wikidata:Q82494858

Synonyms:64732-34-9;(4-methylphenyl)methanesulfonamide;4-methylbenzylsulfonamide;p-tolylmethanesulfonamide;1-(4-methylphenyl)methanesulfonamide;Benzenemethanesulfonamide, 4-methyl-;SCHEMBL3229364;DTXSID20599022;PGMSWUZCYBDABQ-UHFFFAOYSA-N;AKOS009142240;AB87836;FS-2130;AM101079;DB-037959;DB-300689;EN300-200069;F8885-5267

Suppliers and Price of (4-Methylphenyl)methanesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(4-methylphenyl)methanesulfonamide
50mg
$ 65.00

American Custom Chemicals Corporation
4-METHYLBENZYLSULFONAMIDE 95.00%
5MG
$ 504.98

AK Scientific
1-(4-Methylphenyl)methanesulfonamide
100mg
$ 258.00

ACHEMBLOCK
(4-methylphenyl)methanesulfonamide 95%
5G
$ 1815.00

ACHEMBLOCK
(4-methylphenyl)methanesulfonamide 95%
1G
$ 725.00

Total 7 raw suppliers

Chemical Property of (4-Methylphenyl)methanesulfonamide

Chemical Property:

Boiling Point:355.1±45.0 °C(Predicted)
PKA:10.39±0.60(Predicted)
PSA：68.54000
Density:1.262±0.06 g/cm3(Predicted)
LogP:2.56460
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:185.05104977
Heavy Atom Count:12
Complexity:222

Purity/Quality:

98% ^*data from raw suppliers

(4-methylphenyl)methanesulfonamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)CS(=O)(=O)N

Technology Process of (4-Methylphenyl)methanesulfonamide

There total 4 articles about (4-Methylphenyl)methanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51419-59-1
4-methylbenzylsulfonyl chloride

: 64732-34-9
1-(4-methylphenyl)methanesulfonamide

Guidance literature:: With ammonium hydroxide; ammonium carbonate; In tetrahydrofuran; at 20 ℃; for 1h;
DOI:10.1021/acs.jmedchem.8b01971

Reference yield:

: 3395-88-8
4-methylbenzyl methyl ether

: 61017-18-3
O-(methylsulfonyl)hydroxylamine

: 64732-34-9
1-(4-methylphenyl)methanesulfonamide

Guidance literature:: With sodium acetate; In water; at 20 ℃; for 12h;

Reference yield:

: 104-82-5
4-Methylbenzyl chloride

: 64732-34-9
1-(4-methylphenyl)methanesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / 1 h / Reflux

2: hydrogenchloride; N-chloro-succinimide / acetonitrile / 0.33 h / 10 - 20 °C

3: ammonium hydroxide; ammonium carbonate / tetrahydrofuran / 1 h / 20 °C

With hydrogenchloride; ammonium hydroxide; N-chloro-succinimide; ammonium carbonate; In tetrahydrofuran; ethanol; acetonitrile;
DOI:10.1021/acs.jmedchem.8b01971