methyl N-acetyl-N-[{5-bromo-2-[(2-chlorobenzoyl)amino]phenyl}(phenyl)methyl]glycinate

Base Information

• Chemical Name: methyl N-acetyl-N-[{5-bromo-2-[(2-chlorobenzoyl)amino]phenyl}(phenyl)methyl]glycinate
• CAS No.: 5807-03-4
• Molecular Formula: C25H22BrClN2O4
• Molecular Weight: 529.8102
• DSSTox Substance ID: DTXSID20386717
• ChEMBL ID: CHEMBL4475736

Synonyms:CHEMBL4475736;5807-03-4;AC1MFDYA;CBMicro_005078;ChemDiv2_000348;Oprea1_079926;Oprea1_519276;DTXSID20386717;HMS1369P18;SMSF0007951;BDBM50533699;STK533166;AKOS000669426;AKOS021986867;CB07444;BIM-0005089.P001;SR-01000414305;SR-01000414305-1;methyl N-acetyl-N-[{5-bromo-2-[(2-chlorobenzoyl)amino]phenyl}(phenyl)methyl]glycinate;methyl N-acetyl-N-[(5-bromo-2-{[(2-chlorophenyl)carbonyl]amino}phenyl)(phenyl)methyl]glycinate

Chemical Property of methyl N-acetyl-N-[{5-bromo-2-[(2-chlorobenzoyl)amino]phenyl}(phenyl)methyl]glycinate

Chemical Property:

• Vapor Pressure: 2.8E-14mmHg at 25°C
• Boiling Point: 598.4°C at 760 mmHg
• Flash Point: 315.7°C
• Density: 1.443g/cm³
• XLogP3: 5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 528.04515
• Heavy Atom Count: 33
• Complexity: 687

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)N(CC(=O)OC)C(C1=CC=CC=C1)C2=C(C=CC(=C2)Br)NC(=O)C3=CC=CC=C3Cl

Technology Process of methyl N-acetyl-N-[{5-bromo-2-[(2-chlorobenzoyl)amino]phenyl}(phenyl)methyl]glycinate

There total 4 articles about methyl N-acetyl-N-[{5-bromo-2-[(2-chlorobenzoyl)amino]phenyl}(phenyl)methyl]glycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

morpholine (110-91-8,99108-56-2) + 2-chloroethanal (107-20-0) + potassium cyanide (151-50-8) → 2-morpholin-4-yl-acrylonitrile (5807-03-4)

Guidance literature:

morpholine; 2-chloroethanal; In water; at 20 ℃; for 2h;

potassium cyanide; With triethylamine; In water;

DOI:10.3390/90700527

Reference yield:

3-Chloro-2-morpholin-4-yl-propionitrile → 2-morpholin-4-yl-acrylonitrile (5807-03-4)

Guidance literature:

With base; Yield given;

DOI:10.1016/S0040-4020(01)96404-X

Reference yield:

chloroacetaldehyde dimethyl acetal (97-97-2) + sodium cyanide (143-33-9,25596-52-5) + morpholin hydrochloride (10024-89-2) → 2-morpholin-4-yl-acrylonitrile (5807-03-4)

Guidance literature:

With hydrogenchloride;

DOI:10.1021/jo01363a619

upstream raw materials:

chloroacetaldehyde dimethyl acetal

sodium cyanide

morpholin hydrochloride

morpholine

Downstream raw materials:

rel-(1R,4R,9R)-1-Benzoyl-1,4-dihydro-9-morpholino-1,4-ethanonaphthalene-9-carbonitrile

(1R,8R)-1-Benzoyl-9-morpholin-4-yl-tricyclo[6.2.2.0^2,7]dodeca-2,4,6,11-tetraene-9-carbonitrile

4-[3-(3-Chloro-phenyl)-3H-[1,2,3]triazol-4-yl]-morpholine

4-(3-p-Tolyl-3H-[1,2,3]triazol-4-yl)-morpholine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 5807-03-4 methyl N-acetyl-N-[(5-bromo-2-{[(2-chlorophenyl)carbonyl]amino}phenyl)(phenyl)methyl]glycinate

Send

Send

Metric Ton KG G Pound L ML

Send

Send