97-97-2

Basic information

• Product Name: Chloroacetaldehyde dimethyl acetal
• Synonyms: 2-Chlor-1,1-dimethoxyethan;CHLORACETALDEHYDDIMETHYLACETAL;2-Chloro-1,1-dimethoxyethane, Dimethyl chloroacetal;2-Chloro-1,1-dimethoxyethane, CADMA, Dimethyl chloroacetal;2,2-Dimethoxyethyl chloride;Chloroacetaldehyde dimethyl acetal,97%;Chloroacetaldehyde d;Chloroacetaldehyde diMethyl acetal, 97% 250ML
• CAS NO: 97-97-2
• Molecular Formula: C₄H₉ClO₂
• Molecular Weight: 124.57
• EINECS: 202-624-0
• Product Categories: Pyridines ,Halogenated Heterocycles;Pharmaceutical Intermediates
• Mol File: 97-97-2.mol
• Article Data: 10

Chemical Properties

• Melting Point: -73 °C
• Boiling Point: 128-130 °C(lit.)
• Flash Point: 84 °F
• Appearance: Clear colorless to yellow/Liquid
• Density: 1.094 g/mL at 25 °C(lit.)
• Vapor Pressure: 13.494mmHg at 25°C
• Refractive Index: n20/D 1.415(lit.)
• Storage Temp.: Flammables area
• Solubility: 52g/l
• Explosive Limit: 2.3%(V)
• Water Solubility: 52 g/L (20 ºC)
• Sensitive: Moisture Sensitive
• BRN: 1733700
• CAS DataBase Reference: Chloroacetaldehyde dimethyl acetal(CAS DataBase Reference)
• NIST Chemistry Reference: Chloroacetaldehyde dimethyl acetal(97-97-2)
• EPA Substance Registry System: Chloroacetaldehyde dimethyl acetal(97-97-2)

Safety Data

• Hazard Codes: Xn,F
• Statements: 10-22-52/53-20/21/22-40-36/37/38
• Safety Statements: 28A-26-16-36-23
• RIDADR: UN 1989 3/PG 3
• WGK Germany: 2
• F: 1
• TSCA: Yes
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 97-97-2(Hazardous Substances Data)

Usage

Uses

Chloroacetaldehyde dimethyl acetal can be used as a reactant to synthesize:2-(chloromethyl)-4,7-dethyl-1,3-dioxepane2-(chloromethyl)-5,6-benzo-1,3-dioxepane ketene dimethyl acetal

General Description

Chloroacetaldehyde dimethyl acetal is a clear, colorless liquid. It reacts with hydroxythiol to form hydroxy acetal.

Purification Methods

Purify the acetal by fractional distillation. [Melhotra J Indian Chem Soc 36 4405 1959, Beilstein 1 IV 3134.]

InChI:InChI=1/C4H9ClO2/c1-6-4(3-5)7-2/h4H,3H2,1-2H3

Upstream product

• 67-56-1 methanol 
• 108-05-4 vinyl acetate 
• 41683-62-9 1,2-dichloro-1-methoxy-ethane 
• 107-25-5 methoxyethene 
• 124-41-4 sodium methylate 
• 123-63-7 paracetaldehyde 
• 75-07-0 acetaldehyde 
• 10257-28-0 D-Galactose 
• 2280-44-6 D-Glucose 
• 75-01-4 chloroethylene 
• 107-20-0 2-chloroethanal 
• 95684-29-0 2-chloro-1-hydroxyethyl 2-chloro-1-methoxyethyl peroxide 

Downstream Products

• 100388-92-9 2-chloromethyl-4-o-tolyloximethyl-[1,3]dioxolane 
• 775343-47-0 (3-phenyl-propylamino)-acetaldehyde dimethylacetal 
• 86410-02-8 1,1-dimethoxy-2-(p-tolylsulfonyl)ethane 
• 5807-03-4 2-morpholin-4-yl-acrylonitrile 
• 6304-94-5 benzylmercaptoacetaldehyde dimethyl acetal 
• 15890-65-0 bis-(2,2-dimethoxy-ethyl)-disulfane 
• 6443-91-0 ethynyl methyl ether 
• 22483-09-6 2,2-dimethoxyethylamine 
• 53484-82-5 2-methoxy-[1,4]oxathiane 
• 6538-93-8 5,6-dihydro-1,4-oxathiine 
• 2568-30-1 2-chloromethyl-1,3-dioxolane 
• 98544-93-5 butyl-(2,2-dimethoxy-ethyl)-amine 
• 26972-56-5 2-(phenylamino)acetaldehyde dimethyl acetal 
• 62810-43-9 1-bromo-3-(2,2-dimethoxyethoxy)benzene 

Relevant articles and documents

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Method for preparing aminoacetaldehyde dimethyl acetal

The invention discloses a method for preparing aminoacetaldehyde dimethyl acetal, which comprises the following steps: S1, adding a phase transfer catalyst A and vinyl acetate into a reaction flask, introducing a certain amount of chlorine while stirring, and performing heat-insulation stirring until the color of the reaction solution becomes colorless to obtain a chlorination solution; S2, dropwise adding the chlorination liquid prepared in the step S1 into methanol for reaction to prepare a chloroacetaldehyde dimethyl acetal crude product; S3, transferring the chloroacetaldehyde dimethyl acetal crude product prepared in the step S2 to an autoclave, introducing liquid ammonia, carrying out heating and pressurizing reaction, and after the reaction is finished, adding alkali to adjust the pH value; and S4, decompressing and rectifying the reaction product to obtain the target product, aminoacetaldehyde dimethyl acetal. By adopting the method, high-purity aminoacetaldehyde dimethyl acetal can be prepared, and the industrial production requirement of aminoacetaldehyde dimethyl acetal can be met.

Green process technology for preparing chloroacetaldehyde dimethyl acetal from vinyl chloride

The invention discloses a green process technology for preparing chloroacetaldehyde dimethyl acetal from vinyl chloride. The process comprises the following steps: carrying out electrophilic additionreaction and nucleophilic substitution reaction in a tower-type reactor by using chloroethylene, absolute methanol and chlorine as raw materials; sodium methoxide is used as an acid-binding agent, hydrogen chloride generated in the reaction process is neutralized in time, sodium chloride with low solubility is generated and gradually gathered to the bottom of a tower, the concentration of chlorineanions in a reaction system is greatly reduced, and generation of a byproduct 1, 1, 2-trichloroethane is avoided. The method is convenient to control, high in yield, few in side reaction, single in product, convenient to separate and purify, green and pollution-free; and the solvent methanol can be recovered by directly adopting rectification, and the recovered methanol can be repeatedly used.