1-(4-Bromophenyl)-3-(4-methoxyphenyl)propan-1-one

Base Information

• Chemical Name: 1-(4-Bromophenyl)-3-(4-methoxyphenyl)propan-1-one
• CAS No.: 648903-46-2
• Molecular Formula: C16H15BrO2
• Molecular Weight: 319.19300
• Hs Code.: 2914700090
• DSSTox Substance ID: DTXSID80459613
• Nikkaji Number: J1.969.280I
• Wikidata: Q82283429
• Mol file: 648903-46-2.mol

Synonyms:648903-46-2;4'-BROMO-3-(4-METHOXYPHENYL)PROPIOPHENONE;1-(4-bromophenyl)-3-(4-methoxyphenyl)propan-1-one;MFCD03843161;DTXSID80459613;AKOS009339595;1-(4-Bromophenyl)-3-(4-methoxyphenyl)-1-propanone

Chemical Property of 1-(4-Bromophenyl)-3-(4-methoxyphenyl)propan-1-one

Chemical Property:

• Vapor Pressure: 7.08E-08mmHg at 25°C
• Boiling Point: 438.1oC at 760 mmHg
• Flash Point: 218.8oC
• PSA: 26.30000
• Density: 1.339g/cm3
• LogP: 4.27320
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 318.02554
• Heavy Atom Count: 19
• Complexity: 277

Purity/Quality:

97% ^*data from raw suppliers

4'-bromo-3-(4-methoxyphenyl)propiophenone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)CCC(=O)C2=CC=C(C=C2)Br

Technology Process of 1-(4-Bromophenyl)-3-(4-methoxyphenyl)propan-1-one

There total 10 articles about 1-(4-Bromophenyl)-3-(4-methoxyphenyl)propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-methoxy-4-(methoxymethyl)benzene (1515-81-7) + para-bromoacetophenone (99-90-1) → 1-(4-bromophenyl)-3-(4-methoxyphenyl)propan-1-one (648903-46-2)

Guidance literature:

With 2,6-dimethylpyridine; trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at 0 - 20 ℃; for 16h; Inert atmosphere;

DOI:10.1016/j.tetlet.2014.07.068

Reference yield: 92.0%

para-bromoacetophenone (99-90-1) + 4-Methoxybenzyl alcohol (105-13-5) → 1-(4-bromophenyl)-3-(4-methoxyphenyl)propan-1-one (648903-46-2)

Guidance literature:

With C₃₁H₃₆ClN₄Ru⁽¹⁺⁾*F₆P^(1-); potassium hydroxide; In toluene; at 120 ℃; Reagent/catalyst;

DOI:10.1002/cctc.202000254

Reference yield: 90.0%

4-chlorobenzoyl chloride (586-75-4) → 1-(4-bromophenyl)-3-(4-methoxyphenyl)propan-1-one (648903-46-2)

Guidance literature:

With iron(III)-acetylacetonate; In tetrahydrofuran; at -78 ℃;

DOI:10.1021/jo0498866

upstream raw materials:

4'-bromo-4-methoxy-trans-chalcone

4-chlorobenzoyl chloride

3-(4-methoxyphenyl)-1-(4-bromophenyl)-2-propen-1-one

para-bromoacetophenone

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 648903-46-2 4'-BROMO-3-(4-METHOXYPHENYL)PROPIOPHENONE

Send

Send

Metric Ton KG G Pound L ML

Send

Send