Benzoic acid, 2,4-dichloro-3-(triethylsilyl)-, methyl ester

Base Information

Chemical Name:Benzoic acid, 2,4-dichloro-3-(triethylsilyl)-, methyl ester
CAS No.:650598-49-5
Molecular Formula:C14H20Cl2O2Si
Molecular Weight:319.303
Hs Code.:
DSSTox Substance ID:DTXSID70462797
Wikidata:Q82287393

Synonyms:650598-49-5;Benzoic acid, 2,4-dichloro-3-(triethylsilyl)-, methyl ester;DTXSID70462797;AKOS024264315

Suppliers and Price of Benzoic acid, 2,4-dichloro-3-(triethylsilyl)-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Benzoic acid, 2,4-dichloro-3-(triethylsilyl)-, methyl ester

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:6
Exact Mass:318.0609618
Heavy Atom Count:19
Complexity:300

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC[Si](CC)(CC)C1=C(C=CC(=C1Cl)C(=O)OC)Cl

Technology Process of Benzoic acid, 2,4-dichloro-3-(triethylsilyl)-, methyl ester

There total 8 articles about Benzoic acid, 2,4-dichloro-3-(triethylsilyl)-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 650598-47-3
2,4-dichloro-3-(triethylsilyl)benzoic acid

: 650598-49-5
2,4-dichloro-3-(triethylsilyl)benzoic acid methyl ester

Guidance literature:: In diethyl ether;
DOI:10.1002/ejoc.200500553

Reference yield: 74.0%

: 650598-48-4
6-bromo-2,4-dichloro-3-(triethylsilyl)benzoic acid

: 74-88-4
methyl iodide

: 650598-49-5
2,4-dichloro-3-(triethylsilyl)benzoic acid methyl ester

Guidance literature:: 6-bromo-2,4-dichloro-3-(triethylsilyl)benzoic acid; methyl iodide; With tri-n-butyl-tin hydride; potassium carbonate; at 60 ℃; for 12h;

With azobisisobutyronitrile; In benzene; at 60 ℃; for 3h;
DOI:10.1002/ejoc.200300355

Reference yield:

: 994-30-9
triethylsilyl chloride

: 650598-49-5
2,4-dichloro-3-(triethylsilyl)benzoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / BuLi / hexane; tetrahydrofuran / -75 °C

2: 90 percent / t-BuLi / pentane; diethyl ether / -100 °C

3: 95 percent / diethyl ether

With n-butyllithium; tert.-butyl lithium; In tetrahydrofuran; diethyl ether; hexane; pentane;
DOI:10.1002/ejoc.200500553