(R)-N-Formyl-1-(4-methoxyphenyl)ethanamine

Base Information

Chemical Name:(R)-N-Formyl-1-(4-methoxyphenyl)ethanamine
CAS No.:650608-21-2
Molecular Formula:C10H13NO2
Molecular Weight:179.219
Hs Code.:
DSSTox Substance ID:DTXSID60355184
Nikkaji Number:J3.489.488D
Wikidata:Q82133905

Synonyms:650608-21-2;(R)-N-Formyl-1-(4-methoxyphenyl)ethanamine;ZINC00295632;DTXSID60355184;AKOS019938539

Suppliers and Price of (R)-N-Formyl-1-(4-methoxyphenyl)ethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (R)-N-Formyl-1-(4-methoxyphenyl)ethanamine

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:179.094628657
Heavy Atom Count:13
Complexity:153

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=C(C=C1)OC)NC=O
Isomeric SMILES:C[C@H](C1=CC=C(C=C1)OC)NC=O

Technology Process of (R)-N-Formyl-1-(4-methoxyphenyl)ethanamine

There total 3 articles about (R)-N-Formyl-1-(4-methoxyphenyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

: 83834-91-7,1215015-13-6
N-formyl 1-(4-methoxyphenyl)ethylamine

: (S)-N-formyl 1-(4-methoxyphenyl)ethylamine

: 650608-21-2
(R)-N-formyl 1-(4-methoxyphenyl)ethylamine

Guidance literature:: With (S)-N-formyl-1-phenylethylamine; Resolution of racemate;
DOI:10.1016/j.tetlet.2013.07.061

Reference yield:

: 64-18-6
formic acid

: 6298-96-0,22038-86-4,35600-82-9,41851-59-6
1(R)-(4-methoxyphenyl)-ethylamine

: 650608-21-2
(R)-N-formyl 1-(4-methoxyphenyl)ethylamine

Guidance literature:: formic acid; With acetic anhydride; In dichloromethane; at 0 ℃; for 0.5h;

1(R)-(4-methoxyphenyl)-ethylamine; In dichloromethane; at 20 ℃;
DOI:10.1016/j.bmc.2018.04.010

Reference yield:

: 6298-96-0
1-(4-methoxyphenyl)ethanamine

: (S)-N-formyl 1-(4-methoxyphenyl)ethylamine

: 650608-21-2
(R)-N-formyl 1-(4-methoxyphenyl)ethylamine

Guidance literature:: Multi-step reaction with 2 steps

1: trimethylaluminum / toluene; hexane / 1.5 h / 0 - 20 °C

2: (S)-N-formyl-1-phenylethylamine / Resolution of racemate

With trimethylaluminum; (S)-N-formyl-1-phenylethylamine; In hexane; toluene;
DOI:10.1016/j.tetlet.2013.07.061