1H-Indole-3-dodecanol, 5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-

Base Information

Chemical Name:1H-Indole-3-dodecanol, 5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-
CAS No.:651331-72-5
Molecular Formula:C28H39NO5S
Molecular Weight:501.687
Hs Code.:
DSSTox Substance ID:DTXSID60458205
Wikidata:Q82281389

Synonyms:651331-72-5;1H-Indole-3-dodecanol, 5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-;SCHEMBL5371298;DTXSID60458205

Suppliers and Price of 1H-Indole-3-dodecanol, 5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1H-Indole-3-dodecanol, 5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-

Chemical Property:

XLogP3:7.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:16
Exact Mass:501.25489452
Heavy Atom Count:35
Complexity:673

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)S(=O)(=O)N2C=C(C3=C2C=CC(=C3)OC)CCCCCCCCCCCCO

Technology Process of 1H-Indole-3-dodecanol, 5-methoxy-1-[(4-methoxyphenyl)sulfonyl]-

There total 12 articles about 1H-Indole-3-dodecanol, 5-methoxy-1-[(4-methoxyphenyl)sulfonyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 651331-72-5
12-[5-methoxy-1-(4-methoxybenzsulfonyl)-1H-indole-3-yl]-dodecane-1-ol

Guidance literature:

Reference yield: 83.0%

: 3-(12-benzyloxy-1-dodecenyl)-5-methoxy-1-(4-methoxybenzsulfonyl)-1H-indole

: 651331-72-5
12-[5-methoxy-1-(4-methoxybenzsulfonyl)-1H-indole-3-yl]-dodecane-1-ol

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; under 760 Torr;
DOI:10.1021/jm0493616

Reference yield:

: 1006-94-6
5-methoxylindole

: 651331-72-5
12-[5-methoxy-1-(4-methoxybenzsulfonyl)-1H-indole-3-yl]-dodecane-1-ol

Guidance literature:: Multi-step reaction with 4 steps

1.1: 90 percent / phosphoryl chloride / 0 - 40 °C

2.1: NaOH / CH₂Cl₂ / 20 °C

2.2: 95 percent / CH₂Cl₂ / 20 °C

3.1: n-BuLi / tetrahydrofuran; hexane / 0 °C

3.2: potassium tert-butoxide / tetrahydrofuran; hexane / 0 °C

3.3: 62 percent / tetrahydrofuran; hexane / -78 - 0 °C

4.1: 83 percent / H₂ / Pd/C / ethanol / 20 °C / 760 Torr

With sodium hydroxide; n-butyllithium; hydrogen; trichlorophosphate; palladium on activated charcoal; In tetrahydrofuran; ethanol; hexane; dichloromethane; 1.1: Vilsmeier formylation / 3.3: Wittig reaction;
DOI:10.1021/jm0493616