Chemical Property of 5-Methoxyindole-2-carboxylic acid
Chemical Property:
- Appearance/Colour:light yellow to brownish powder
- Vapor Pressure:8.54E-09mmHg at 25°C
- Melting Point:199-201 °C
- Refractive Index:1.5310 (estimate)
- Boiling Point:447.6 °C at 760 mmHg
- PKA:4.38±0.30(Predicted)
- Flash Point:224.5 °C
- PSA：62.32000
- Density:1.381 g/cm3
- LogP:1.87470
- Storage Temp.:Refrigerator
- XLogP3:2.3
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:2
- Exact Mass:191.058243149
- Heavy Atom Count:14
- Complexity:231
- Purity/Quality:
-
99% *data from raw suppliers
5-Methoxyindole-2-carboxylic Acid *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- Safety Statements:
22-24/25
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:COC1=CC2=C(C=C1)NC(=C2)C(=O)O
-
Uses
Reactant for preparation of:? ;Anticancer agents1? ;A fluorescent small molecule probe for in vivo lipid imaging2? ;Indoleamine 2,3-dioxygenase (IDO) inhibitors3? ;Selective Dopamine D3 receptor ligands4? ;5-HT4 receptor ligands5? ;Inhibitors of Mycobacterium tuberculosis pantothenate synthetase6? ;Hypoxia selective cytotoxins7? ;Potent antitumor bifunctional DNA alkylating agents8 5-Methoxyindole-2-carboxylic Acid is a very useful synthetic intermediate. It is a reactant used to prepare anticancer agents, Indoleamine 2,3-dioxygenase (IDO) inhibitors, and potent antitumor bifunctional DNA alkylating agents. Reactant for preparation of:Anticancer agentsA fluorescent small molecule probe for in vivo lipid imagingIndoleamine 2,3-dioxygenase (IDO) inhibitorsSelective Dopamine D3 receptor ligands5-HT4 receptor ligandsInhibitors of Mycobacterium tuberculosis pantothenate synthetaseHypoxia selective cytotoxinsPotent antitumor bifunctional DNA alkylating agents
