Dimethyl-(2-piperidin-2-yl-ethyl)-amine

Base Information

• Chemical Name: Dimethyl-(2-piperidin-2-yl-ethyl)-amine
• CAS No.: 60717-49-9
• Molecular Formula: C9H20N2
• Molecular Weight: 156.27
• Hs Code.: 2933399090
• NSC Number: 166306
• DSSTox Substance ID: DTXSID60304571
• Mol file: 60717-49-9.mol

Synonyms:60717-49-9;Dimethyl-(2-piperidin-2-yl-ethyl)-amine;N,N-dimethyl-2-piperidin-2-ylethanamine;N,N-dimethyl-2-(piperidin-2-yl)ethanamine;2-(2-Dimethylaminoethyl)piperidine;dimethyl[2-(piperidin-2-yl)ethyl]amine;NSC166306;F3297-0021;SCHEMBL4148616;DTXSID60304571;VQWPLEFSACXKNE-UHFFFAOYSA-N;BBL028015;MFCD00047329;STK711111;2-(2-dimethylamino-ethyl)-piperidine;2-[2-(dimethylamino)ethyl]piperidine;AKOS000270720;AKOS016040094;NSC-166306;SB41121;rac.-2-(2-dimethylaminoethyl)piperidine;BP-11214;rac-2-(2-(dimethylamino)ethyl)piperidine;VS-08645;CS-0206097;FT-0677942;EN300-122589;A868903;Z336087874

Chemical Property of Dimethyl-(2-piperidin-2-yl-ethyl)-amine

Chemical Property:

• Vapor Pressure: 0.348mmHg at 25°C
• Boiling Point: 199.1°C at 760 mmHg
• PKA: 10.47±0.10(Predicted)
• Flash Point: 58.7°C
• PSA: 15.27000
• Density: 0.866g/cm³
• LogP: 1.40900
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 156.162648646
• Heavy Atom Count: 11
• Complexity: 102

Purity/Quality:

97% ^*data from raw suppliers

N,N-Dimethyl-2-(2-piperidinyl)ethanamineDihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCC1CCCCN1

Technology Process of Dimethyl-(2-piperidin-2-yl-ethyl)-amine

There total 4 articles about Dimethyl-(2-piperidin-2-yl-ethyl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-<-(dimethylamino)ethyl>pyridine (6304-27-4) → 2-(2-Dimethylamino-ethyl)-piperidin (60717-49-9)

Guidance literature:

With acetic acid; platinum; at 60 ℃; under 2206.5 Torr; Hydrogenation;

DOI:10.1021/ja01564a063

Reference yield:

dimethyl amine (124-40-3) → 2-(2-Dimethylamino-ethyl)-piperidin (60717-49-9)

Guidance literature:

With ethanol; at 120 - 130 ℃;

DOI:10.1021/ja01564a063

Reference yield:

2-vinylpyridine (100-69-6,25014-15-7,27476-03-5,329041-71-6) → 2-(2-Dimethylamino-ethyl)-piperidin (60717-49-9)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroquinone / 140 - 150 °C

2: platinum; acetic acid / 60 °C / 2206.5 Torr / Hydrogenation

With acetic acid; hydroquinone; platinum;

DOI:10.1021/ja01564a063

upstream raw materials:

2-<-(dimethylamino)ethyl>pyridine

dimethyl amine

2-vinylpyridine