2-Isopropylpyridine 1-oxide

Base Information

Chemical Name:2-Isopropylpyridine 1-oxide
CAS No.:65257-53-6
Molecular Formula:C8H11NO
Molecular Weight:137.181
Hs Code.:
DSSTox Substance ID:DTXSID50524569
Wikidata:Q82391530

Synonyms:65257-53-6;2-isopropylpyridine-N-oxide;2-Isopropylpyridine 1-oxide;SCHEMBL996540;DTXSID50524569;VJYVBCPJWGIGFV-UHFFFAOYSA-N;1-Oxo-2-(propan-2-yl)-1lambda~5~-pyridine

Suppliers and Price of 2-Isopropylpyridine 1-oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-Isopropylpyridine 1-oxide

Chemical Property:

XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:137.084063974
Heavy Atom Count:10
Complexity:103

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1=CC=CC=[N+]1[O-]

Technology Process of 2-Isopropylpyridine 1-oxide

There total 1 articles about 2-Isopropylpyridine 1-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₀H₁₄NO₂⁽¹⁺⁾*C₂₄H₂₀B^(1-)

: 26708-23-6
4-(4'-N,N-dimethylaminostyryl)pyridine N-oxide

: 65257-53-6
2-isopropylpyridine N-oxide

: 1-acetyloxy-4-(4'-N,N-dimethylaminostyryl)pyridinium tetraphenylborate

Guidance literature:: In acetonitrile; at 24.84 ℃; Equilibrium constant;
DOI:10.1134/S1070363208060248

Reference yield: 74.0%

: 65257-53-6
2-isopropylpyridine N-oxide

: 7677-24-9
trimethylsilyl cyanide

: 337904-76-4
6-isopropylpyridine-2-carbonitrile

Guidance literature:: 2-isopropylpyridine N-oxide; trimethylsilyl cyanide; In 1,2-dichloro-ethane; at 20 ℃; for 0.0833333h;

With N,N-diethylcarbamyl chloride; In 1,2-dichloro-ethane; at 20 ℃; for 48h;

Reference yield:

: 65257-53-6
2-isopropylpyridine N-oxide

: (S)-1-(diphenylphosphanyl)-2-(6-isopropylpyridin-2-yl)-1,2,3,4-tetrahydroquinoline

Guidance literature:: Multi-step reaction with 5 steps

1.1: N,N-Dimethylcarbamoyl chloride / dichloromethane / 12 h / 25 °C / Inert atmosphere

2.1: tetrahydrofuran; diethyl ether / -25 - 20 °C / Inert atmosphere

2.2: 4.17 h / 0 - 20 °C / Inert atmosphere

3.1: potassium hydroxide / ethanol / 3 h / 85 °C / Inert atmosphere

4.1: Ru(OSO₂CF₃)(C₆(CH₃)6)(NH₂CHC₆H₅CHC₆H₅NSO₂C₆H₄CH₃); hydrogen / isopropyl alcohol / 12 h / 25 °C / 38002.6 Torr / Autoclave

5.1: triethylamine / dichloromethane / 1 h / 0 °C / Inert atmosphere

5.2: 0 - 20 °C / Inert atmosphere

With Ru(OSO₂CF₃)(C₆(CH₃)6)(NH₂CHC₆H₅CHC₆H₅NSO₂C₆H₄CH₃); hydrogen; triethylamine; potassium hydroxide; N,N-Dimethylcarbamoyl chloride; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; isopropyl alcohol;
DOI:10.1039/c9ob00770a