Benzenecarbothioic acid, S-(4,6-diamino-2-pyrimidinyl) ester

Base Information

• Chemical Name: Benzenecarbothioic acid, S-(4,6-diamino-2-pyrimidinyl) ester
• CAS No.: 65349-39-5
• Molecular Formula: C11H10N4OS
• Molecular Weight: 246.293
• Mol file: 65349-39-5.mol

Synonyms:

Chemical Property of Benzenecarbothioic acid, S-(4,6-diamino-2-pyrimidinyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenecarbothioic acid, S-(4,6-diamino-2-pyrimidinyl) ester

There total 3 articles about Benzenecarbothioic acid, S-(4,6-diamino-2-pyrimidinyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4,6-diamino-1-benzoylamino-1H-pyrimidine-2-thione (65349-40-8) → 2-benzoylthio-4,6-diaminopyrimidine (65349-39-5)

Guidance literature:

In acetonitrile; for 0.05h; Heating;

DOI:10.1007/BF00949231

Reference yield: 80.0%

benzoyl chloride (98-88-4) + 4,6-diamino-2-mercaptopyrimidine (1004-39-3) → 2-benzoylthio-4,6-diaminopyrimidine (65349-39-5)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

DOI:10.1007/BF00951232

Reference yield:

→ 2-benzoylthio-4,6-diaminopyrimidine (65349-39-5)

Guidance literature:

Aus Verb. /BRN= 750236/ + CH3CN (5h Kochen);

upstream raw materials:

benzoyl chloride

4,6-diamino-2-mercaptopyrimidine

4,6-diamino-1-benzoylamino-1H-pyrimidine-2-thione

Downstream raw materials:

N-(6-Amino-2-thioxo-1,2-dihydro-pyrimidin-4-yl)-benzamide

4,6-diamino-1-benzoylamino-1H-pyrimidine-2-thione

4,6-diamino-2-mercaptopyrimidine

Refernces

• 1、 Podzigun, G. I.,Pashkurov, N. G.,Reznik, V. S.,Ivanov, B. E.. "CHEMICAL PROPERTIES OF ACYLATED DERIVATIVES OF 4,6-DIAMINO-2-MERCAPTOPYRIMIDINE". . p. 1820 - 1823. Retrieved 2007/10/02.