1-Propanone, 3-(dimethylamino)-1-[3-(trifluoromethyl)phenyl]-

Base Information

Chemical Name:1-Propanone, 3-(dimethylamino)-1-[3-(trifluoromethyl)phenyl]-
CAS No.:653573-36-5
Molecular Formula:C12H14F3NO
Molecular Weight:245.244
Hs Code.:
DSSTox Substance ID:DTXSID80451430
Wikidata:Q82271452

Synonyms:653573-36-5;1-Propanone, 3-(dimethylamino)-1-[3-(trifluoromethyl)phenyl]-;SCHEMBL7899079;DTXSID80451430;XBPDAKZKYMDZJH-UHFFFAOYSA-N;AKOS017547694;3-dimethylamino-1-(3-trifluoromethylphenyl)-propan-1-one

Suppliers and Price of 1-Propanone, 3-(dimethylamino)-1-[3-(trifluoromethyl)phenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-Propanone, 3-(dimethylamino)-1-[3-(trifluoromethyl)phenyl]-

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:245.10274856
Heavy Atom Count:17
Complexity:263

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCC(=O)C1=CC(=CC=C1)C(F)(F)F

Technology Process of 1-Propanone, 3-(dimethylamino)-1-[3-(trifluoromethyl)phenyl]-

There total 2 articles about 1-Propanone, 3-(dimethylamino)-1-[3-(trifluoromethyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 653573-36-5
3-(dimethylamino)-1-(3-(trifluoromethyl)phenyl)propan-1-one

Guidance literature:: With hydrogenchloride; In ethanol; Reflux;

With sodium hydroxide; In water; at 0 ℃;

Reference yield:

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 506-59-2
N,N-dimethylammonium chloride

: 170141-63-6
1-(3-trifluoromethoxy-phenyl)ethanone

: 653573-36-5
3-(dimethylamino)-1-(3-(trifluoromethyl)phenyl)propan-1-one

Guidance literature:: With hydrogenchloride; In ethanol; water; at 90 ℃; for 18h; Sealed tube;
DOI:10.1016/j.bmcl.2017.10.042

Reference yield: 79.0%

: 653573-36-5
3-(dimethylamino)-1-(3-(trifluoromethyl)phenyl)propan-1-one

: 6-bromo-3-(furan-2-ylmethyl)-2-methoxyquinoline

: C₂₇H₂₆BrF₃N₂O₃

Guidance literature:: 6-bromo-3-(furan-2-ylmethyl)-2-methoxyquinoline; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 ℃; for 1.5h;

3-(dimethylamino)-1-(3-(trifluoromethyl)phenyl)propan-1-one; In tetrahydrofuran; hexane; at -78 ℃; for 3h;
DOI:10.1016/j.bmcl.2017.10.042