N-{2-[2,2-Di(1H-indol-3-yl)ethyl]phenyl}acetamide

Base Information

Chemical Name:N-{2-[2,2-Di(1H-indol-3-yl)ethyl]phenyl}acetamide
CAS No.:6548-01-2
Molecular Formula:C26H23N3O
Molecular Weight:393.488
Hs Code.:
ChEMBL ID:CHEMBL4995569
DSSTox Substance ID:DTXSID20495212
Wikidata:Q82343184

Synonyms:6548-01-2;acetamide,n-[2-(2,2-di-1h-indol-3-ylethyl)phenyl]-;N-{2-[2,2-Di(1H-indol-3-yl)ethyl]phenyl}acetamide;CHEMBL4995569;DTXSID20495212;1-acetamido-2-[2,2-di(3-indolyl)ethyl]benzene

Suppliers and Price of N-{2-[2,2-Di(1H-indol-3-yl)ethyl]phenyl}acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N-{2-[2,2-Di(1H-indol-3-yl)ethyl]phenyl}acetamide

Chemical Property:

XLogP3:5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:5
Exact Mass:393.184112366
Heavy Atom Count:30
Complexity:563

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC=CC=C1CC(C2=CNC3=CC=CC=C32)C4=CNC5=CC=CC=C54

Technology Process of N-{2-[2,2-Di(1H-indol-3-yl)ethyl]phenyl}acetamide

There total 9 articles about N-{2-[2,2-Di(1H-indol-3-yl)ethyl]phenyl}acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.0%

: 120-72-9
indole

: 75-36-5
acetyl chloride

: 576-15-8
N-acetylindole

: 17537-64-3
1,3-diacetyl-1H-indole

: 6548-01-2
3,3'-(o-acetamidophenethylidene)di-indole

Guidance literature:: With triethylamine; In dichloromethane; for 1h; Heating;
DOI:10.1016/S0040-4020(98)00865-5

Reference yield:

: 1969-73-9
(2-nitrophenyl)acetaldehyde

: 6548-01-2
3,3'-(o-acetamidophenethylidene)di-indole

Guidance literature:: Multi-step reaction with 3 steps

1: 0.82 percent / acetic acid / 2 h / 105 °C

2: 0.04 percent / H₂ / Raney Ni / methanol / Ambient temperature

3: 0.52 percent / 0.05 h / 108 °C

With hydrogen; nickel; In methanol; acetic acid;

Reference yield:

: 15582-86-2
methyl o-nitrostyrylcarbamate

: 6548-01-2
3,3'-(o-acetamidophenethylidene)di-indole

Guidance literature:: Multi-step reaction with 4 steps

1: 0.19 percent / 20 percent H₂SO₄ / 1 h / Heating

2: 0.82 percent / acetic acid / 2 h / 105 °C

3: 0.04 percent / H₂ / Raney Ni / methanol / Ambient temperature

4: 0.52 percent / 0.05 h / 108 °C

With sulfuric acid; hydrogen; nickel; In methanol; acetic acid;