2-chloro-N-(2-formyl-1H-indol-3-yl)-N-(4-nitrophenyl)acetamide

Base Information

Chemical Name:2-chloro-N-(2-formyl-1H-indol-3-yl)-N-(4-nitrophenyl)acetamide
CAS No.:658041-39-5
Molecular Formula:C17H12ClN3O4
Molecular Weight:357.753
Hs Code.:
DSSTox Substance ID:DTXSID60396754
Wikidata:Q82197638
ChEMBL ID:CHEMBL1334919

Synonyms:2-chloro-N-(2-formyl-1H-indol-3-yl)-N-(4-nitrophenyl)acetamide;658041-39-5;MLS000333032;SMR000436326;2-Chloro-N-(2-formyl-1H-indol-3-yl)-N-(4-nitro-phenyl)-acetamide;CHEMBL1334919;BDBM50687;cid_3810898;DTXSID60396754;STL040926;AKOS005694383;SR-01000761076;SR-01000761076-2;2-chloranyl-N-(2-methanoyl-1H-indol-3-yl)-N-(4-nitrophenyl)ethanamide

Suppliers and Price of 2-chloro-N-(2-formyl-1H-indol-3-yl)-N-(4-nitrophenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-chloro-N-(2-formyl-1H-indol-3-yl)-N-(4-nitrophenyl)acetamide

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:357.0516336
Heavy Atom Count:25
Complexity:519

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=C(N2)C=O)N(C3=CC=C(C=C3)[N+](=O)[O-])C(=O)CCl

Technology Process of 2-chloro-N-(2-formyl-1H-indol-3-yl)-N-(4-nitrophenyl)acetamide

There total 3 articles about 2-chloro-N-(2-formyl-1H-indol-3-yl)-N-(4-nitrophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 79-04-9
chloroacetyl chloride

: 167954-14-5
3-[N-(4-nitrophenyl)amino]-2-formylindole

: 658041-39-5
2-formyl-3-[N'-(ω-chloroacetyl)-N'-(4-nitrophenyl)amino]indole

Guidance literature:: With sodium carbonate; In toluene; for 3h; Heating;
DOI:10.1023/A:1024887429776

Reference yield:

: 167954-19-0
3-[N-(4-nitrophenyl)amino]indole

: 658041-39-5
2-formyl-3-[N'-(ω-chloroacetyl)-N'-(4-nitrophenyl)amino]indole

Guidance literature:: Multi-step reaction with 3 steps

1: 67 percent / POCl₃ / 3.5 h / 20 °C

2: water

3: 98 percent / Na₂CO₃ / toluene / 3 h / Heating

With water; sodium carbonate; trichlorophosphate; In toluene; 1: Vilsmeier reaction;
DOI:10.1023/A:1024887429776

Reference yield:

: 2-diimethyliminomeethyl-3-[N-(4-nitrophenyl)amino]indole chloride

: 658041-39-5
2-formyl-3-[N'-(ω-chloroacetyl)-N'-(4-nitrophenyl)amino]indole

Guidance literature:: Multi-step reaction with 2 steps

1: water

2: 98 percent / Na₂CO₃ / toluene / 3 h / Heating

With water; sodium carbonate; In toluene;
DOI:10.1023/A:1024887429776