1,8-Naphthyridine-2,7-dicarbaldehyde

Base Information

Chemical Name:1,8-Naphthyridine-2,7-dicarbaldehyde
CAS No.:65896-28-8
Molecular Formula:C10H6N2O2
Molecular Weight:186.17
Hs Code.:
DSSTox Substance ID:DTXSID80497015
Nikkaji Number:J1.403.710A
Wikidata:Q82346305
Mol file:65896-28-8.mol

Synonyms:1,8-naphthyridine-2,7-dicarbaldehyde;65896-28-8;SCHEMBL3421490;DTXSID80497015;AC9537;MFCD24674090;SY251295;EN300-5067682

Suppliers and Price of 1,8-Naphthyridine-2,7-dicarbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
1,8-Naphthyridine-2,7-dicarbaldehyde
1g
$ 1268.00

Total 6 raw suppliers

Chemical Property of 1,8-Naphthyridine-2,7-dicarbaldehyde

Chemical Property:

Melting Point:225-227 °C
Boiling Point:408.6±40.0 °C(Predicted)
PKA:-0.63±0.30(Predicted)
PSA：59.92000
Density:1.396±0.06 g/cm3(Predicted)
LogP:1.25480
XLogP3:1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:186.042927438
Heavy Atom Count:14
Complexity:210

Purity/Quality:

99% ^*data from raw suppliers

1,8-Naphthyridine-2,7-dicarbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=NC2=C1C=CC(=N2)C=O)C=O

Technology Process of 1,8-Naphthyridine-2,7-dicarbaldehyde

There total 7 articles about 1,8-Naphthyridine-2,7-dicarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 14903-78-7
2,7-dimethyl-[1,8]naphthyridine

: 65896-28-8
1,8-naphthyridine-2,7-dicarboxaldehyde

Guidance literature:: With selenium(IV) oxide; In 1,4-dioxane; for 0.2h; Heating; microwave;
DOI:10.1081/SCC-120015779

Reference yield:

: 1824-81-3
2-Amino-6-methylpyridine

: 65896-28-8
1,8-naphthyridine-2,7-dicarboxaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: H₂O / 3 h / cooling

1.2: 30 percent oleum; nitrobenzene / 0.5 h / 110 °C

1.3: 37 percent / NaOH / H₂O / 1 h / pH 10 / cooling

2.1: 59 percent / SeO₂; molecular sieves 4 Angstroem / dioxane / 2 h / Heating

With selenium(IV) oxide; 4 A molecular sieve; In 1,4-dioxane; water; 1.2: Skraup synthesis;
DOI:10.1002/jhet.5570390432

Reference yield:

: 84670-41-7
2,7-dimethyl-4-chloro-1,8-naphthyridine

: 65896-28-8
1,8-naphthyridine-2,7-dicarboxaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: H₂; KOH / Pd/CaCO₃ / 760 Torr

2: SeO₂ / dioxane

With potassium hydroxide; selenium(IV) oxide; hydrogen; Lindlar's catalyst; In 1,4-dioxane; 1: Hydrogenation / 2: Oxidation;
DOI:10.1016/S0040-4020(00)00748-1