Acetamide, N-[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]-

Base Information

Chemical Name:Acetamide, N-[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]-
CAS No.:65902-08-1
Molecular Formula:C12H15NO
Molecular Weight:189.257
Hs Code.:
DSSTox Substance ID:DTXSID50465044
Nikkaji Number:J1.018.041D
Wikidata:Q82290703

Synonyms:65902-08-1;(S)-N-(1,2,3,4-Tetrahydronaphthalen-1-yl)acetamide;N-[(1S)-1,2,3,4-tetrahydronaphthalen-1-yl]acetamide;Acetamide, N-[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]-;SCHEMBL8340594;DTXSID50465044;DZKCMVGYTDZOLO-LBPRGKRZSA-N;(S)-N-(1,2,3,4-tetrahydro-1-naphthyl)acetamide

Suppliers and Price of Acetamide, N-[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Acetamide, N-[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]-

Chemical Property:

PSA：32.59000
LogP:3.04040
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:189.115364102
Heavy Atom Count:14
Complexity:214

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1CCCC2=CC=CC=C12
Isomeric SMILES:CC(=O)N[C@H]1CCCC2=CC=CC=C12

Technology Process of Acetamide, N-[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]-

There total 2 articles about Acetamide, N-[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

: 2217-40-5
1,2,3,4-tetrahydronaphthalen-1-amine

: 141-78-6
ethyl acetate

: 23357-52-0
(S)-1,2,3,4-tetrahydronapht-1-yl-amine

: 65902-08-1
(S)-N-(1,2,3,4-tetrahydro-naphthalen-1-yl)acetamide

: (R)-(+)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

Guidance literature:: With Candida antarctica lipase B; In di-isopropyl ether; at 60 ℃;
DOI:10.1021/jo026701r

Reference yield:

: 2217-40-5
1,2,3,4-tetrahydronaphthalen-1-amine

: 498542-91-9
(1S,2S)-N-acetyl-1,2-bis(trifluoromethanesulfonamido) cyclohexane

: 23357-52-0
(S)-1,2,3,4-tetrahydronapht-1-yl-amine

: 23357-46-2
(R)-1,2,3,4-Tetrahydro-1-naphthylamine

: 65902-08-1
(S)-N-(1,2,3,4-tetrahydro-naphthalen-1-yl)acetamide

: (R)-(+)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)acetamide

Guidance literature:: With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; at -20 ℃; for 24h; Title compound not separated from byproducts;
DOI:10.1002/anie.200453956

Reference yield: 86.0%

: 85-44-9
phthalic anhydride

: 65902-08-1
(S)-N-(1,2,3,4-tetrahydro-naphthalen-1-yl)acetamide

: 60925-92-0
(S)-2-(1,2,3,4-tetrahydronaphthalen-1-yl)isoindoline-1,3-dione

Guidance literature:: (S)-N-(1,2,3,4-tetrahydro-naphthalen-1-yl)acetamide; With pyridine; oxalyl dichloride; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

With propylene glycol; In tetrahydrofuran; at 0 - 20 ℃; for 1.5h; Inert atmosphere;

phthalic anhydride; With pyridine; In toluene; for 16h; Reflux;
DOI:10.1021/ol802482d