6,7-Dihydroxyflavone

Base Information

Chemical Name:6,7-Dihydroxyflavone
CAS No.:38183-04-9
Molecular Formula:C15H10O4
Molecular Weight:254.242
Hs Code.:2914400090
European Community (EC) Number:805-262-7
UNII:P6R86H59XS
DSSTox Substance ID:DTXSID60191569
Nikkaji Number:J456.651C
Wikidata:Q83064100
Pharos Ligand ID:MYKFC2Z2N3AK
Metabolomics Workbench ID:74505
ChEMBL ID:CHEMBL300814
Mol file:38183-04-9.mol

Synonyms:6,7-dihydroxyflavone;7,8-dihydroxyflavone

Suppliers and Price of 6,7-Dihydroxyflavone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6,7-Dihydroxyflavone
5mg
$ 125.00

Biosynth Carbosynth
6,7-Dihydroxyflavone
25 mg
$ 100.00

Biosynth Carbosynth
6,7-Dihydroxyflavone
10 mg
$ 50.00

Biosynth Carbosynth
6,7-Dihydroxyflavone
50 mg
$ 175.00

American Custom Chemicals Corporation
6,7-DIHYDROXYFLAVONE 95.00%
100MG
$ 582.12

AK Scientific
6,7-Dihydroxyflavone
25mg
$ 185.00

AK Scientific
6,7-Dihydroxyflavone
10mg
$ 117.00

Total 20 raw suppliers

Chemical Property of 6,7-Dihydroxyflavone

Chemical Property:

Vapor Pressure:1.69E-11mmHg at 25°C
Melting Point:251-254 °C
Refractive Index:1.698
Boiling Point:521.6 °C at 760 mmHg
PKA:6.86±0.40(Predicted)
Flash Point:204.8 °C
PSA：70.67000
Density:1.443 g/cm³
LogP:2.87120
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:254.05790880
Heavy Atom Count:19
Complexity:384

Purity/Quality:

97% ^*data from raw suppliers

6,7-Dihydroxyflavone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=O)C3=CC(=C(C=C3O2)O)O
Uses 6,7-Dihydroxyflavone is a useful compound for the preparation of chromenone derivatives introduced with biphenyl for prevention or treatment of allergic diseases.

Technology Process of 6,7-Dihydroxyflavone

There total 11 articles about 6,7-Dihydroxyflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 38183-04-9
6,7-dihydroxyflavone

Guidance literature:: With boron tribromide; In dichloromethane; for 12h; Inert atmosphere; Reflux;

Reference yield: 32.0%

: 533-73-3
1,2,4-Trihydroxybenzene

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 38183-04-9
6,7-dihydroxyflavone

Guidance literature:: In diphenylether; for 4h; Heating;
DOI:10.1271/bbb.68.369

Reference yield:

: 525-82-6,66585-04-4
FLAVONE

: 2196-14-7
7,4'-Dihydroxyflavon

: 38183-04-9
6,7-dihydroxyflavone

: 38183-03-8
7,8-dihydroxyflavone

Guidance literature:: Multi-step reaction with 2 steps

1: cytochromes P₄₅₀ in human liver microsomes / Enzymatic reaction

2: cytochromes P₄₅₀ in human liver microsomes / Enzymatic reaction

With cytochromes P₄₅₀ in human liver microsomes;
DOI:10.5562/cca3528