(1R)-2-Methylcyclohex-2-en-1-ol

Base Information

• Chemical Name: (1R)-2-Methylcyclohex-2-en-1-ol
• CAS No.: 6610-16-8
• Molecular Formula: C7H12O
• Molecular Weight: 112.172
• DSSTox Substance ID: DTXSID00499718
• Nikkaji Number: J1.850.037J
• Wikidata: Q82350748
• Mol file: 6610-16-8.mol

Synonyms:(1R)-2-Methylcyclohex-2-en-1-ol;6610-16-8;SCHEMBL26205945;DTXSID00499718

Chemical Property of (1R)-2-Methylcyclohex-2-en-1-ol

Chemical Property:

• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 112.088815002
• Heavy Atom Count: 8
• Complexity: 105

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CCCCC1O
• Isomeric SMILES: CC1=CCCC[C@H]1O

Technology Process of (1R)-2-Methylcyclohex-2-en-1-ol

There total 6 articles about (1R)-2-Methylcyclohex-2-en-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-methyl-2-cyclohexen-1-one (1121-18-2) → (R)-(+)-2-methyl-2-cyclohexen-1-ol (6610-16-8)

Guidance literature:

With benzo[1,3,2]dioxaborole; Oxazaborolidine 2; In toluene; at -78 ℃; for 15h;

DOI:10.1016/S0040-4039(00)94581-7

Reference yield: 82.0%

2-methyl-2-cyclohexen-1-one (1121-18-2) → (R)-(+)-2-methyl-2-cyclohexen-1-ol (6610-16-8,20461-30-7,76888-40-9,87422-11-5)

Guidance literature:

With 2-(ethylamino)pyridine; lithium aluminium tetrahydride; (-)-N-methylephedrine; In diethyl ether; at -78 ℃; for 3h;

Reference yield: 29.0%

2-methylcyclohex-2-en-1-ol (20461-30-7) → 2-methyl-2-cyclohexen-1-one (1121-18-2) + (R)-(+)-2-methyl-2-cyclohexen-1-ol (6610-16-8) + 2-Methylcyclohexanone (583-60-8) + (S)-2-methyl-1-cyclohexen-3-ol (76888-40-9)

Guidance literature:

With D-glucose; Yamadazyma farinosa IFO 10896; In phosphate buffer; at 30 ℃; for 0.5h; pH=6.5; Further byproducts. Title compound not separated from byproducts.;

DOI:10.1246/cl.2007.1428

upstream raw materials:

2-methyl-2-cyclohexen-1-one

2-methylcyclohex-2-en-1-ol

1-methylcyclohex-1-ene

Downstream raw materials:

(S)-1,6-dimethyl-1-cyclohexene

(1R,2S,6S)-1,6-dimethylcyclohexane-1,2-dicarboxylic acid

(1S,2R,3S)-2-(hydroxymethyl-2,3-dimethylcyclohexyl)methanol

(1R,2S,6S)-1,2-bis-iodomethyl-1,6-dimethylcyclohexane