(Z)-3-(4-AMino-3,5-diMethylphenyl)acrylonitrile

Base Information Edit

Chemical Name:(Z)-3-(4-AMino-3,5-diMethylphenyl)acrylonitrile
CAS No.:661489-22-1
Molecular Formula:C11H12N2
Molecular Weight:172.22600
Hs Code.:
Mol file:661489-22-1.mol

Synonyms:(2Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile;

Suppliers and Price of (Z)-3-(4-AMino-3,5-diMethylphenyl)acrylonitrile

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile
100mg
$ 575.00

Biosynth Carbosynth
(Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile
2 mg
$ 139.90

Biosynth Carbosynth
(Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile
50 mg
$ 1529.00

Biosynth Carbosynth
(Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile
25 mg
$ 841.00

Biosynth Carbosynth
(Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile
5 mg
$ 254.40

Biosynth Carbosynth
(Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile
10 mg
$ 462.50

AK Scientific
2-Propenenitrile,3-(4-amino-3,5-dimethylphenyl)-,(2E)-
5mg
$ 393.00

AK Scientific
2-Propenenitrile,3-(4-amino-3,5-dimethylphenyl)-,(2E)-
2mg
$ 238.00

Total 5 raw suppliers

Chemical Property of (Z)-3-(4-AMino-3,5-diMethylphenyl)acrylonitrile Edit

Chemical Property:

Boiling Point:355.5±30.0 °C(Predicted)
PKA:3.74±0.10(Predicted)
PSA：49.81000
Density:1.085±0.06 g/cm3 (20 oC 760 Torr)
LogP:3.00358
Solubility.:Acetone, Dichloromethane, Methanol, Toluene

Purity/Quality:

99.3% ^*data from raw suppliers

(Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (Z)-3-(4-Amino-3,5-dimethylphenyl)acrylonitrile is a pharmaceutical intermediate of Rivilpirine (R509800), a novel non-nucleoside reverse transcriptase inhibitor.

Technology Process of (Z)-3-(4-AMino-3,5-diMethylphenyl)acrylonitrile

There total 22 articles about (Z)-3-(4-AMino-3,5-diMethylphenyl)acrylonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 749249-96-5
C₁₁H₁₀N₂O₂

: 500292-94-4,500292-86-4,661489-22-1
trans-3-(4-amino-3,5-dimethylphenyl)acrylonitrile

Guidance literature:: With ammonium chloride; iron; In tetrahydrofuran; methanol; water; at 50 ℃; for 4h;

Reference yield: 87.0%

: 500292-92-2
(2E)-3-(4-amino-3,5-dimethylphenyl)prop-2-enamide

: 500292-94-4,500292-86-4,661489-22-1
trans-3-(4-amino-3,5-dimethylphenyl)acrylonitrile

Guidance literature:: (2E)-3-(4-amino-3,5-dimethylphenyl)prop-2-enamide; With trichlorophosphate; at 20 ℃;

With sodium hydrogencarbonate; In water; ethyl acetate;