1-DODECANOYLPYRROLIDINE

Base Information

• Chemical Name: 1-DODECANOYLPYRROLIDINE
• CAS No.: 70974-45-7
• Molecular Formula: C16H31 N O
• Molecular Weight: 253.428
• Mol file: 70974-45-7.mol

Synonyms:Pyrrolidine,1-(1-oxododecyl)- (9CI); 1-Dodecanoylpyrrolidine; N-Dodecanoylpyrrolidine; NSC60381

Chemical Property of 1-DODECANOYLPYRROLIDINE

Chemical Property:

• Vapor Pressure: 8.32E-06mmHg at 25°C
• Boiling Point: 152-154°C 0,8mm
• Flash Point: 153.5°C
• PSA: 20.31000
• Density: 0.917g/cm³
• LogP: 4.46760

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

1-DODECANOYLPYRROLIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-DODECANOYLPYRROLIDINE

There total 1 articles about 1-DODECANOYLPYRROLIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyrrolidine (123-75-1) → 1-(pyrrolidin-1-yl)dodecan-1-one (70974-45-7)

Guidance literature:

With potassium carbonate; In chloroform; water;

DOI:10.1002/jps.2600751114

Reference yield: 70.0%

n-butyl magnesium bromide (693-03-8) + 1-(pyrrolidin-1-yl)dodecan-1-one (70974-45-7) → hexadecan-5-one (41903-81-5)

Guidance literature:

1-(pyrrolidin-1-yl)dodecan-1-one; With 2,6-di-tert-butyl-4-methylpyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at -78 - 0 ℃; for 2h; Inert atmosphere;

n-butyl magnesium bromide; In diethyl ether; dichloromethane; at -78 ℃; for 2h; chemoselective reaction; Inert atmosphere;

DOI:10.1016/j.tet.2015.04.074

Reference yield:

N-butylacetamide (1119-49-9) + 1-(pyrrolidin-1-yl)dodecan-1-one (70974-45-7) → 1-Benzylamino-5-methyl-2,4,6,8-tetraoxo-3,7-dioxa-2λ5,4λ5,6λ5,8λ5-tetraphospha-bicyclo[3.3.1]nonane-2,4,6,8-tetraol (145336-34-1) + Monocyclic 1-benzylaminodecane-1,1,3,3-tetrayl-tetrakis-phosphonic anhydride (145361-49-5)

Guidance literature:

With pyridine; hydrogenchloride; water; phosphorus trichloride; Yield given. Multistep reaction. Yields of byproduct given; 1) o-dichlorobenzene, a) 81-82 deg C, 4 h, b) 91-92 deg C, 4 h, 2) 15 h, reflux;

upstream raw materials:

pyrrolidine

Downstream raw materials:

1-Benzylamino-5-methyl-2,4,6,8-tetraoxo-3,7-dioxa-2λ⁵,4λ⁵,6λ⁵,8λ⁵-tetraphospha-bicyclo[3.3.1]nonane-2,4,6,8-tetraol

Monocyclic 1-benzylaminodecane-1,1,3,3-tetrayl-tetrakis-phosphonic anhydride

1-Butylamino-5-methyl-2,4,6,8-tetraoxo-3,7-dioxa-2λ⁵,4λ⁵,6λ⁵,8λ⁵-tetraphospha-bicyclo[3.3.1]nonane-2,4,6,8-tetraol

hexadecan-5-one