41903-81-5Relevant articles and documents
Tf2O/TTBP (2,4,6-Tri-tert-butylpyrimidine): An Alternative Amide Activation System for the Direct Transformations of Both Tertiary and Secondary Amides
He, Qian,Ye, Jian-Liang,Xu, Fang-Fang,Geng, Hui,Chen, Ting-Ting,Chen, Hang,Huang, Pei-Qiang
, (2021/09/28)
Ten types of Tf2O/TTBP-mediated amide transformation reactions were investigated. The results showed that compared with pyridine derivatives 2,6-di-tert-butyl-4-methylpyridine (DTBMP) and 2-fluoropyridine (2-F-Pyr.), TTBP can serve as an alternative amide activation system for the direct transformation of both secondary and tertiary amides. For most surveyed examples, higher or comparable yields were generally obtained. In addition, Tf2O/TTBP combination was used to promote the condensation reactions of 2-(tert-butyldimethylsilyloxy)furan (TBSOF) with both tertiary and secondary amides, the one-pot reductive Bischler-Napieralski-type reaction of tertiary lactams, and Movassaghi and Hill's modern version of the Bischler-Napieralski reaction. The value of the Tf2O/TTBP-based methodology was further demonstrated by the concise and high-yielding syntheses of several natural products.
A new vanadium(IV)-bridged polyoxotungstate containing mixed valence-antimony(III,V)
Wang, Bin,Xu, Ling-Xiao,Meng, Rui-Qi,Suo, Lin,Li, Bao,Wu, Li-Xin,Bi, Li-Hua
, p. 274 - 278 (2013/10/22)
A new mixed-valence SbV/III containing vanadium-substituted polyoxotungstate Na10[{SbV(OH)3} 2{VIV-O(H2O)}2{Sb IIIW9O33}2]·32H2O (1-Na) has been synthesized by routine synthetic reaction and characterized by IR, XPS, elemental analysis. The polyoxoanion [{SbV(OH)3}2{V IVO(H2O)}2{SbIIIW9O33}2]10 (1) consists of two trilacunary species β-B-SbIIIW9O 33 connected by two VIVO(H2O) groups and two SbV(OH)3 units. The cyclic voltammetry and catalytic activity of 1-Na for the oxidation of n-hexadecane under green condition have been measured.
Convenient Synthesis of Functionalized Dialkyl Ketones and Alkanoylsilanes: 1-(Benzotriazol-1-yl)-1-phenoxyalkanes as Alkanoyl Anion Equivalents
Katritzky, Alan R.,Lang, Hengyuan,Wang, Zuoquan,Lie, Zhu
, p. 7551 - 7557 (2007/10/03)
(Benzotriazol-1-yl)-1-phenoxyalkanes 10, prepared by two-step transformations of the corresponding aldehydes, are readily deprotonated at the methine group by BuLi.Subsequent reactions with alkyl halides, aldehydes, ketones, and imines yield the corresponding substituted derivatives that undergo hydrolysis under acidic conditions to afford the expected functionalized ketones 13, 15, 17, 19, 21, 24 and 25.Two successive lithiations of (benzotriazolyl)phenoxymethane, each followed by reaction with a trialkylsilyl chloride, alkyl halide, aldehyde, or ketone, generate similar intermediates 27, 39, 31, 33, and 36.Subsequent hydrolyses of 27, 29, 31, 33, and 36 yield the functionalized ketones 28, 30, and 32 and the alkanoylsilanes 34 and 37 in good yields.