2-Phenyl-4-thiazolidinecarboxamide monohydrochloride

Base Information

Chemical Name:2-Phenyl-4-thiazolidinecarboxamide monohydrochloride
CAS No.:106086-20-8
Molecular Formula:C10H12 N2 O S . Cl H
Molecular Weight:244.741
Hs Code.:
DSSTox Substance ID:DTXSID80909901

Synonyms:2-Phenyl-4-thiazolidinecarboxamide monohydrochloride;106086-20-8;4-Thiazolidinecarboxamide, 2-phenyl-, monohydrochloride;2-Phenylthiazolidine-4-carboxylic acid amide hydrochloride;DTXSID80909901;LS-151159;2-Phenyl-1,3-thiazolidine-4-carboximidic acid--hydrogen chloride (1/1)

Suppliers and Price of 2-Phenyl-4-thiazolidinecarboxamide monohydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Phenyl-4-thiazolidinecarboxamide monohydrochloride

Chemical Property:

Vapor Pressure:4.01E-09mmHg at 25°C
Boiling Point:473.2°Cat760mmHg
Flash Point:240°C
Density:g/cm³
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:244.0437119
Heavy Atom Count:15
Complexity:216

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(NC(S1)C2=CC=CC=C2)C(=O)N.Cl

Technology Process of 2-Phenyl-4-thiazolidinecarboxamide monohydrochloride

There total 4 articles about 2-Phenyl-4-thiazolidinecarboxamide monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 106086-14-0
N-tert-Butyloxycarbonyl-2-phenylthiazolidine-4-carboxylic acid amide

: 106086-20-8
2-Phenylthiazolidine-4-carboxylic acid amide hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 10 ℃;
DOI:10.1007/BF01148643

Reference yield:

: 196930-46-8
(4R)-2-phenyl-1,3-thiazolidine-4-carboxylic acid

: 106086-20-8
2-Phenylthiazolidine-4-carboxylic acid amide hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 93 percent / Et₃N / dimethylformamide / 2 h / Ambient temperature

2: 81 percent / pyridine / dimethylformamide / 2 h / Ambient temperature

3: 85 percent / NH₃ / methanol / 1.5 h / Ambient temperature

4: 85 percent / HCl / dioxane / 10 °C

With pyridine; hydrogenchloride; ammonia; triethylamine; In 1,4-dioxane; methanol; N,N-dimethyl-formamide;
DOI:10.1007/BF01148643

Reference yield:

: 106086-10-6
(4R)-3-(tert-butoxycarbonyl)-2-phenylthiazolidine-4-carboxylic acid

: 106086-20-8
2-Phenylthiazolidine-4-carboxylic acid amide hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 81 percent / pyridine / dimethylformamide / 2 h / Ambient temperature

2: 85 percent / NH₃ / methanol / 1.5 h / Ambient temperature

3: 85 percent / HCl / dioxane / 10 °C

With pyridine; hydrogenchloride; ammonia; In 1,4-dioxane; methanol; N,N-dimethyl-formamide;
DOI:10.1007/BF01148643