1-[2-(Trifluoromethyl)phenyl]piperazin-1-ium;chloride

Base Information

• Chemical Name: 1-[2-(Trifluoromethyl)phenyl]piperazin-1-ium;chloride
• CAS No.: 40160-26-7
• Molecular Formula: C11H13 F3 N2 . Cl H
• Molecular Weight: 266.694
• European Community (EC) Number: 254-814-8
• Mol file: 40160-26-7.mol

Synonyms:40160-26-7;1-[2-(trifluoromethyl)phenyl]piperazin-1-ium;chloride;1-[2-(TRIFLUOROMETHYL)PHENYL]PIPERAZINIUM CHLORIDE;1-(o-Trifluoromethylphenyl) piperazine (hydrochloride);1-[2-(TRIFLUOROMETHYL)PHENYL]PIPERAZIN-1-IUM CHLORIDE;1-(2-(Trifluoromethyl)phenyl)piperazinium chloride

Chemical Property of 1-[2-(Trifluoromethyl)phenyl]piperazin-1-ium;chloride

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 15.27000
• Density: g/cm³
• LogP: 3.31080
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 266.0797606
• Heavy Atom Count: 17
• Complexity: 224

Purity/Quality:

99% ,98%,Electron Grade , ^*data from raw suppliers

1-[2-(Trifluoromethyl)phenyl]-piperazineMonohydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C[NH+](CCN1)C2=CC=CC=C2C(F)(F)F.[Cl-]
• Uses: 1-[2-(Trifluoromethyl)phenyl]-piperazine Monohydrochloride is a reference standard and a related compound of Piperazine (P480100), an anthelmintic.

Technology Process of 1-[2-(Trifluoromethyl)phenyl]piperazin-1-ium;chloride

There total 1 articles about 1-[2-(Trifluoromethyl)phenyl]piperazin-1-ium;chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

tert-butyl 4-(2-(trifluoromethyl)-phenyl)piperazine-1-carboxylate (1121596-52-8) → 1-(2-(trifluoromethyl)phenyl)piperazine hydrochloride (40160-26-7)

Guidance literature:

With hydrogenchloride; In diethyl ether; dichloromethane; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1021/acs.jmedchem.5b00423

Reference yield: 91.0%

2-(4-bromobutyl)isoindoline-1,3-dione (5394-18-3) + 1-(2-(trifluoromethyl)phenyl)piperazine hydrochloride (40160-26-7) → 2-[4-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]butyl]isoindoline-1,3-dione

Guidance literature:

With potassium carbonate; In acetonitrile; for 6h; Reflux;

DOI:10.1021/acs.jmedchem.6b01578

Reference yield: 63.0%

1-(2-(trifluoromethyl)phenyl)piperazine hydrochloride (40160-26-7) + methyl 2-chloro-6-methylpyrimidine-4-carboxylate (89793-11-3) → 6-methyl-2-(4-(2-(trifluoromethyl)phenyl)piperazin-1-yl)pyrimidine-4-carboxylate

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 60 ℃; for 16h; Inert atmosphere;

DOI:10.1021/acs.jmedchem.5b00423

upstream raw materials:

tert-butyl 4-(2-(trifluoromethyl)-phenyl)piperazine-1-carboxylate

Downstream raw materials:

C₂₄H₂₈F₃N₃O₂

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 40160-26-7 1-[2-(trifluoromethyl)phenyl]piperazinium chloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send