CYCLOHEXYLPHOSPHONIC DICHLORIDE

Base Information

• Chemical Name: CYCLOHEXYLPHOSPHONIC DICHLORIDE
• CAS No.: 1005-22-7
• Molecular Formula: C6H11 Cl2 O P
• Molecular Weight: 201.033
• Hs Code.: 2931900090
• Mol file: 1005-22-7.mol

Synonyms:Phosphonicdichloride, cyclohexyl- (6CI,7CI,8CI,9CI); Cyclohexanephosphonyl chloride;Cyclohexylphosphonic acid dichloride; Cyclohexylphosphonic dichloride;Cyclohexylphosphonodichloridic acid; Cyclohexylphosphonyl dichloride;Dichlorocyclohexylphosphine oxide

Chemical Property of CYCLOHEXYLPHOSPHONIC DICHLORIDE

Chemical Property:

• Vapor Pressure: 0.0195mmHg at 25°C
• Melting Point: 40-43 °C
• Refractive Index: n20/D 1.506(lit.)
• Boiling Point: 127-129 °C (15 mmHg)
• Flash Point: 111.5°C
• PSA: 26.88000
• Density: 1.296 g/mL at 25 °C(lit.)
• LogP: 3.98980

Purity/Quality:

98%,99%, ^*data from raw suppliers

Cyclohexylphosphonicdichloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 34
• Safety Statements: 45-36/37/39-26-27

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CYCLOHEXYLPHOSPHONIC DICHLORIDE

There total 8 articles about CYCLOHEXYLPHOSPHONIC DICHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

cyclohexylphosphonic acid (1005-23-8) → cyclohexylphosphonic dichloride (1005-22-7)

Guidance literature:

With oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide; Heating;

DOI:10.1016/S0040-4039(00)60798-0

Reference yield: 81.0%

cyclohexyl-phosphonic acid bis-trimethylsilanyl ester (18027-42-4) → chloro-trimethyl-silane (75-77-4) + cyclohexylphosphonic dichloride (1005-22-7)

Guidance literature:

With phosphorus pentachloride; In tetrachloromethane; for 1h; Ambient temperature;

DOI:10.1246/cl.1980.435

Reference yield: 45.0%

cyclohexane (110-82-7,25012-93-5) → cyclohexylphosphonic dichloride (1005-22-7)

Guidance literature:

With oxygen; phosphorus trichloride; at 15 ℃;

DOI:10.1134/S1070363211030066

upstream raw materials:

cyclohexane

cyclohexyl chloride

cyclohexene

cyclohexylphosphonic acid

Downstream raw materials:

cyclohexyl dimethylphosphonate

Cyclohexyl-phosphonic acid diethyl ester

cyclohexyl-phosphonic acid diallyl ester

cyclohexyl-phosphonic acid-dianilide

Refernces

• 1、 Isbell,Wadsworth. "-". . p. 6042,6044. Retrieved 1956.
• 2、 Flurry,Boozer. "-". . p. 2076. Retrieved 1966.
• 3、 Gregson, Aaron M.,Wales, Steven M.,Bailey, Stephen J.,Willis, Anthony C.,Keller, Paul A.. "Cyclic Phosphine Oxides and Phosphinamides from Di-Grignard Reagents and Phosphonic Dichlorides: Modular Access to Annulated Phospholanes". . p. 9774 - 9780. Retrieved 2015/10/12.
• 4、 Rogers, Roland S.. "A general synthesis of phosphonic acid dichlorides using oxalyl chloride and DMF catalysis". . p. 7473 - 7474. Retrieved 2007/10/02.