1-Isopropenyl-3,5-di(trifluoromethyl)benzene

Base Information

Chemical Name:1-Isopropenyl-3,5-di(trifluoromethyl)benzene
CAS No.:66875-48-7
Molecular Formula:C11H8F6
Molecular Weight:254.175
Hs Code.:
DSSTox Substance ID:DTXSID70381616
Wikidata:Q82172539

Synonyms:1-isopropenyl-3,5-di(trifluoromethyl)benzene;66875-48-7;1-prop-1-en-2-yl-3,5-bis(trifluoromethyl)benzene;Benzene, 1-(1-methylethenyl)-3,5-bis(trifluoromethyl)-;MFCD00120045;SCHEMBL20615653;DTXSID70381616;GQZHGPTXTONDEY-UHFFFAOYSA-N;AKOS009158082;1-isopropenyl-3,5-bis(trifluoromethyl)benzene;1-isopropenyl-3,5-bis(trifluoromethyl)-benzene

Suppliers and Price of 1-Isopropenyl-3,5-di(trifluoromethyl)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-Isopropenyl-3,5-di(trifluoromethyl)benzene

Chemical Property:

XLogP3:5.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:254.05301923
Heavy Atom Count:17
Complexity:265

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=C)C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F

Technology Process of 1-Isopropenyl-3,5-di(trifluoromethyl)benzene

There total 4 articles about 1-Isopropenyl-3,5-di(trifluoromethyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.5%

: 67570-38-1
α,α-dimethyl-3,5-bis(trifluoromethyl)benzenemethanol

: 66875-48-7
1-(prop-1-en-2-yl)-3,5-bis(trifluoromethyl)benzene

Guidance literature:: With N,N,N,N,N,N-hexamethylphosphoric triamide; at 240 ℃; for 1.5h;

Reference yield: 64.0%

: 30071-93-3
3,5-bis(trifluoromethyl)phenyl methyl ketone

: 1779-49-3
Methyltriphenylphosphonium bromide

: 66875-48-7
1-(prop-1-en-2-yl)-3,5-bis(trifluoromethyl)benzene

Guidance literature:: Methyltriphenylphosphonium bromide; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 0 ℃; for 0.5h;

3,5-bis(trifluoromethyl)phenyl methyl ketone; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 18h; Inert atmosphere;
DOI:10.1021/jacs.5b02503

Reference yield:

: 328-70-1
3,6-bis(trifluoromethyl)bromobenzene

: 66875-48-7
1-(prop-1-en-2-yl)-3,5-bis(trifluoromethyl)benzene

Guidance literature:: Multi-step reaction with 2 steps

1: 95.1 percent / Mg / diethyl ether / 0.5 h / Ambient temperature

2: 81.5 percent / hexamethylphosphoric triamide / 1.5 h / 240 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; magnesium; In diethyl ether;