2-Chloro-N-(2,6-dimethyl-4-nitrophenyl)acetamide

Base Information

Chemical Name:2-Chloro-N-(2,6-dimethyl-4-nitrophenyl)acetamide
CAS No.:67083-23-2
Molecular Formula:C10H11ClN2O3
Molecular Weight:242.662
Hs Code.:
DSSTox Substance ID:DTXSID70509494
Wikidata:Q82367110

Synonyms:2-Chloro-N-(2,6-dimethyl-4-nitrophenyl)acetamide;67083-23-2;SCHEMBL11650801;DTXSID70509494

Suppliers and Price of 2-Chloro-N-(2,6-dimethyl-4-nitrophenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Chloro-N-(2,6-dimethyl-4-nitrophenyl)acetamide

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:242.0458199
Heavy Atom Count:16
Complexity:268

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=C1NC(=O)CCl)C)[N+](=O)[O-]

Technology Process of 2-Chloro-N-(2,6-dimethyl-4-nitrophenyl)acetamide

There total 5 articles about 2-Chloro-N-(2,6-dimethyl-4-nitrophenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 16947-63-0
2,6-dimethyl-4-nitroaniline

: 79-04-9
chloroacetyl chloride

: 67083-23-2
2-chloro-N-(2,6-dimethyl-4-nitrophenyl)acetamide

Guidance literature:: With triethylamine; In diethyl ether; for 6h; Ambient temperature;
DOI:10.1002/jps.2600710619

Reference yield:

: 87-62-7
2,6-dimethylaniline

: 67083-23-2
2-chloro-N-(2,6-dimethyl-4-nitrophenyl)acetamide

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine / 4 h / 115 °C

2: nitric acid; sodium nitrite; acetic acid / water / 5 h / 110 °C / Inert atmosphere

3: sulfuric acid / 1 h / 60 °C

4: pyridine; triethylamine / dichloromethane / 0 - 20 °C

With pyridine; sulfuric acid; nitric acid; acetic acid; triethylamine; sodium nitrite; In dichloromethane; water;

Reference yield:

: 67083-22-1
N-(2,6-dimethyl-4-nitrophenyl)-4-methylbenzenesulfonamide

: 67083-23-2
2-chloro-N-(2,6-dimethyl-4-nitrophenyl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / 1 h / 60 °C

2: pyridine; triethylamine / dichloromethane / 0 - 20 °C

With pyridine; sulfuric acid; triethylamine; In dichloromethane;