4-(Chloromethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole

Base Information

Chemical Name:4-(Chloromethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole
CAS No.:671216-07-2
Molecular Formula:C14H16ClNO4
Molecular Weight:297.73400
Hs Code.:2934999090
ChEMBL ID:CHEMBL5193841
DSSTox Substance ID:DTXSID20478803
Wikidata:Q82312424
Mol file:671216-07-2.mol

Synonyms:671216-07-2;4-(chloromethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole;4-(Chloromethyl)-2-(3,4,5-trimethoxyphenyl)-5-methyloxazole;4-(chloromethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)Oxazole;SCHEMBL5025927;CHEMBL5193841;DTXSID20478803;PSAFEPFUPOBJFZ-UHFFFAOYSA-N;MFCD10699135;AKOS005255423;BS-9834;BB 0242350;FT-0762104;4-Chloromethyl-5-methyl-2-(3,4,5-trimethoxy- phenyl)-oxazole;4-chloromethyl-5-methyl-2-(3,4,5-trimethoxy-phenyl)-oxazole

Suppliers and Price of 4-(Chloromethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
4-(chloromethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole
100mg
$ 179.00

AK Scientific
4-(chloromethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole
50mg
$ 129.00

AK Scientific
4-(chloromethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole
5mg
$ 59.00

Total 2 raw suppliers

Chemical Property of 4-(Chloromethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole

Chemical Property:

PSA：53.72000
LogP:3.41460
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:297.0767857
Heavy Atom Count:20
Complexity:293

Purity/Quality:

99% ^*data from raw suppliers

4-(chloromethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(N=C(O1)C2=CC(=C(C(=C2)OC)OC)OC)CCl

Technology Process of 4-(Chloromethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole

There total 3 articles about 4-(Chloromethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 832076-80-9
4,5-dimethyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole

: 671216-07-2
4-(chloromethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole

Guidance literature:: With N-chloro-succinimide; In acetonitrile; at 60 ℃;
DOI:10.1055/s-2004-834862

Reference yield:

: 21065-46-3
3,4,5-Trimethoxy-benzoic acid 1-methyl-2-oxo-propyl ester

: 671216-07-2
4-(chloromethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole

Guidance literature:: Multi-step reaction with 2 steps

1: CH₃COONH₄; CH₃COOH / 8 h / Heating

2: 48 percent / N-chlorosuccinimide / acetonitrile / 60 °C

With N-chloro-succinimide; ammonium acetate; acetic acid; In acetonitrile;
DOI:10.1055/s-2004-834862

Reference yield:

: 118-41-2
Eudesmic acid

: 671216-07-2
4-(chloromethyl)-5-methyl-2-(3,4,5-trimethoxyphenyl)-1,3-oxazole

Guidance literature:: Multi-step reaction with 3 steps

1: 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide*HCl; 4-(dimethylamino)pyridine / dimethylformamide / 25 °C

2: CH₃COONH₄; CH₃COOH / 8 h / Heating

3: 48 percent / N-chlorosuccinimide / acetonitrile / 60 °C

With dmap; N-chloro-succinimide; ammonium acetate; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1055/s-2004-834862