21065-46-3Relevant academic research and scientific papers
Palladium-catalyzed selective anti-markovnikov oxidation of allylic esters
Dong, Jia Jia,Fananas-Mastral, Martin,Alsters, Paul L.,Browne, Wesley R.,Feringa, Ben L.
, p. 5561 - 5565 (2013/06/27)
An aldol alternative: The palladium(II)-catalyzed anti-Markovnikov oxidation of allylic esters to aldehydes at room temperature provides a viable alternative to valuable cross aldol products. High regioselectivity towards the aldehyde product was achieved using the ester protecting group for the allylic alcohol. Rapid isomerization and the much higher rate of oxidation of the branched isomer result in the same product forming from both linear and branched allylic esters. Copyright
A new approach to the synthesis of 2-aryl-4-halomethyl-5-methyl-1,3- oxazoles by highly regioselective direct halogenation with NBS or NCS/MeCN
Yamane, Taihei,Mitsudera, Hiroyuki,Shundoh, Takatsugu
, p. 2825 - 2832 (2007/10/03)
A simple and efficient method for the synthesis of 2-aryl-4-bromomethyl-5- methyl-1,3-oxazoles 2 and 2-aryl-4-chloromethyl-5-methyl-1,3-oxazoles 3 is described. The reaction of 2-aryl-4,5-dimethyl-1,3-oxazoles 1 with N-bromosuccinimide and N-chlorosuccini
