2-(2-Bromophenyl)[1,3]oxazolo[5,4-b]pyridine

Base Information

Chemical Name:2-(2-Bromophenyl)[1,3]oxazolo[5,4-b]pyridine
CAS No.:67588-13-0
Molecular Formula:C₁₂H₇BrN₂O
Molecular Weight:275.104
Hs Code.:
ChEMBL ID:CHEMBL3244997
DSSTox Substance ID:DTXSID00499192
Nikkaji Number:J1.264.518J
Wikidata:Q82349757

Synonyms:67588-13-0;2-(2-Bromophenyl)[1,3]oxazolo[5,4-b]pyridine;CHEMBL3244997;DTXSID00499192

Suppliers and Price of 2-(2-Bromophenyl)[1,3]oxazolo[5,4-b]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-(2-Bromophenyl)[1,3]oxazolo[5,4-b]pyridine

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:273.97418
Heavy Atom Count:16
Complexity:251

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=NC3=C(O2)N=CC=C3)Br

Technology Process of 2-(2-Bromophenyl)[1,3]oxazolo[5,4-b]pyridine

There total 4 articles about 2-(2-Bromophenyl)[1,3]oxazolo[5,4-b]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67588-15-2
3-(2'-bromobenzoyl)aminopyrid-2-one

: 67588-13-0
2-(2'-bromophenyl)oxazolo<5,4-b>pyridine

Guidance literature:: With trichlorophosphate;
DOI:10.1021/jm00209a014

Reference yield:

: 6298-19-7
2-chloro-3-aminopyridine

: 67588-13-0
2-(2'-bromophenyl)oxazolo<5,4-b>pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / pyridine / toluene / 1 h / Heating

2: 89 percent / NH₄Cl, polyphosphoric acid / 12 h / 180 °C

3: P₂O₅ / 0.75 h / 200 °C

With pyridine; PPA; phosphorus pentoxide; ammonium chloride; In toluene;
DOI:10.1002/jhet.5570200535

Reference yield:

: 7154-66-7
2-bromobenzoic acid chloride

: 67588-13-0
2-(2'-bromophenyl)oxazolo<5,4-b>pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / pyridine / toluene / 1 h / Heating

2: 89 percent / NH₄Cl, polyphosphoric acid / 12 h / 180 °C

3: P₂O₅ / 0.75 h / 200 °C

With pyridine; PPA; phosphorus pentoxide; ammonium chloride; In toluene;
DOI:10.1002/jhet.5570200535