2,3,5,6-Tetrafluoro-4-phenoxybenzonitrile

Base Information

Chemical Name:2,3,5,6-Tetrafluoro-4-phenoxybenzonitrile
CAS No.:67600-87-7
Molecular Formula:C13H5F4NO
Molecular Weight:267.182
Hs Code.:
DSSTox Substance ID:DTXSID50595537
Nikkaji Number:J1.394.776G
Wikidata:Q82490554

Synonyms:2,3,5,6-Tetrafluoro-4-phenoxybenzonitrile;67600-87-7;4-phenoxy-2,3,5,6-tetrafluorobenzonitrile;SCHEMBL3194044;DTXSID50595537

Suppliers and Price of 2,3,5,6-Tetrafluoro-4-phenoxybenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2,3,5,6-Tetrafluoro-4-phenoxybenzonitrile

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:267.03072643
Heavy Atom Count:19
Complexity:336

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)OC2=C(C(=C(C(=C2F)F)C#N)F)F

Technology Process of 2,3,5,6-Tetrafluoro-4-phenoxybenzonitrile

There total 2 articles about 2,3,5,6-Tetrafluoro-4-phenoxybenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 773-82-0
Pentafluorobenzonitrile

: 108-95-2,27073-41-2
phenol

: 67600-87-7
2,3,5,6-tetrafluoro-4-phenoxybenzonitrile

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; regioselective reaction;
DOI:10.1016/j.jfluchem.2014.03.005

Reference yield: 78.0%

: 773-82-0
Pentafluorobenzonitrile

: 98-80-6
phenylboronic acid

: 67600-87-7
2,3,5,6-tetrafluoro-4-phenoxybenzonitrile

Guidance literature:: With bis(acetylacetonate)nickel(II); potassium phosphate; oxygen; In tetrahydrofuran; for 8h; Inert atmosphere; Reflux;
DOI:10.1039/c2cc33755j