2-Benzyl-3,4-dihydroisoquinolin-1(2H)-one

Base Information

• Chemical Name: 2-Benzyl-3,4-dihydroisoquinolin-1(2H)-one
• CAS No.: 6772-61-8
• Molecular Formula: C16H15NO
• Molecular Weight: 237.301
• DSSTox Substance ID: DTXSID70449306
• Nikkaji Number: J258.771H
• Wikidata: Q82268725

Synonyms:2-Benzyl-3,4-dihydroisoquinolin-1(2H)-one;6772-61-8;2-benzyl-3,4-dihydroisoquinolin-1-one;DTXSID70449306;2-benzyl-3,4-dihydro-1(2H)-isoquinolinone;3,4-Dihydro-2-benzylisoquinolin-1(2H)-one;2-benzyl-1,2,3,4-tetrahydroisoquinolin-1-one;N-benzyl-1,2,3,4-tetrahydroisoquinolin-1-one

Chemical Property of 2-Benzyl-3,4-dihydroisoquinolin-1(2H)-one

Chemical Property:

• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 237.115364102
• Heavy Atom Count: 18
• Complexity: 296

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CN(C(=O)C2=CC=CC=C21)CC3=CC=CC=C3

Technology Process of 2-Benzyl-3,4-dihydroisoquinolin-1(2H)-one

There total 35 articles about 2-Benzyl-3,4-dihydroisoquinolin-1(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-benzyl-1-(2H)-isoquinoline ketone (59168-21-7) → 2-(4-benzylphenyl)-3,4-dihydroisoquinolin-1(2H)-one (6772-61-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; under 2585.7 Torr; Ambient temperature;

DOI:10.1002/jhet.5570320113

Reference yield: 95.0%

methyl 2-((benzyl(phenethyl)carbamoyl)oxy)benzoate → 2-(4-benzylphenyl)-3,4-dihydroisoquinolin-1(2H)-one (6772-61-8)

Guidance literature:

With trifluorormethanesulfonic acid; In dichloromethane; at 25 ℃; for 1h; Inert atmosphere;

DOI:10.1021/acs.joc.9b02843

Reference yield: 84.0%

N-benzyl-1,2,3,4-tetrahydroisoquinoline (13605-95-3) → 2-(4-benzylphenyl)-3,4-dihydroisoquinolin-1(2H)-one (6772-61-8)

Guidance literature:

With sodium chlorite; In 1,1,1-trichloroethane; water; at 55 - 65 ℃; for 2.5h;

DOI:10.1055/s-0032-1316747

upstream raw materials:

2-benzyl-1-(2H)-isoquinoline ketone

N-benzyl-1,2,3,4-tetrahydroisoquinoline

6-Oxo-6H-pyran-2-carboxylic acid benzyl-but-3-enyl-amide

2-vinylbenzoic acid

Downstream raw materials:

N-benzylisoquinoline-1,3,4(2H)-trione

N-benzoyl-homophthalimide

2-benzyl-1-cyano-1,2,3,4-tetrahydroisoquinoline bromide

N-benzyl-1-phenyl-1,2,3,4-tetrahydroisoquinoline

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 6772-61-8 1(2H)-Isoquinolinone, 3,4-dihydro-2-(phenylmethyl)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send