2-Isopropyl-5-isobutylpyrazine

Base Information

Chemical Name:2-Isopropyl-5-isobutylpyrazine
CAS No.:68290-70-0
Molecular Formula:C11H18N2
Molecular Weight:178.27400
Hs Code.:
DSSTox Substance ID:DTXSID80508099
Metabolomics Workbench ID:99807
Wikidata:Q82364804
Mol file:68290-70-0.mol

Synonyms:68290-70-0;2-Isobutyl-5-isopropylpyrazine;2-Isopropyl-5-isobutylpyrazine;2-(2-methylpropyl)-5-propan-2-ylpyrazine;SCHEMBL14580444;DTXSID80508099;CHEBI:215256;UHVOUUJPLVBJAV-UHFFFAOYSA-N;2-(2-Methylpropyl)-5-(propan-2-yl)pyrazine

Suppliers and Price of 2-Isopropyl-5-isobutylpyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-Isopropyl-5-isobutylpyrazine

Chemical Property:

PSA：25.78000
LogP:2.79850
XLogP3:2.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:178.146998583
Heavy Atom Count:13
Complexity:143

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)CC1=CN=C(C=N1)C(C)C

Technology Process of 2-Isopropyl-5-isobutylpyrazine

There total 8 articles about 2-Isopropyl-5-isobutylpyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 76779-97-0
1-azido-3-methylbutan-2-one

: 870544-28-8
1-azido-4-methylpentan-2-one

: 24294-83-5
2,5-bis(1-methylethyl)pyrazine

: 68290-70-0
2-(1-methylethyl)-5-(2-methylpropyl)pyrazine

: 65032-04-4
2,5-bis(2-methylpropyl)pyrazine

Guidance literature:: With triphenylphosphine; In benzene; at 20 ℃; for 24h; Title compound not separated from byproducts;
DOI:10.1002/ejoc.200500280

Reference yield:

: 563-80-4
3-methyl-butan-2-one

: 68290-70-0
2-(1-methylethyl)-5-(2-methylpropyl)pyrazine

Guidance literature:: Multi-step reaction with 4 steps

1.1: MeLi; iPr₂NH / diethyl ether / -78 °C

1.2: 69 percent / diethyl ether / 0.5 h / -90 °C

2.1: 79 percent / bromine / pentane / 0.5 h / -78 °C

3.1: 100 percent / NaN₃ / acetic acid; ethanol; H₂O / 20 h / 0 °C

4.1: PPh₃ / benzene / 24 h / 20 °C

With sodium azide; methyllithium; bromine; diisopropylamine; triphenylphosphine; In diethyl ether; ethanol; water; acetic acid; pentane; benzene;
DOI:10.1002/ejoc.200500280

Reference yield:

: 29585-02-2
1-bromo-4-methyl-2-pentanone

: 68290-70-0
2-(1-methylethyl)-5-(2-methylpropyl)pyrazine

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / NaN₃ / ethanol; H₂O; acetic acid / 20 h / 0 °C

2: PPh₃ / benzene / 24 h / 20 °C

With sodium azide; triphenylphosphine; In ethanol; water; acetic acid; benzene;
DOI:10.1002/ejoc.200500280